Diabetes-specific Quality of Life After a Low-carbohydrate and Low-fat Dietary Intervention

Nichola J. Davis; Nora Tomuta; Carmen R. Isasi; Vivien Leung; Judith Wylie-Rosett

doi:10.1177/0145721711436132

Diabetes-specific Quality of Life After a Low-carbohydrate and Low-fat Dietary Intervention

Nichola J. Davis
, Nora Tomuta
, Carmen R. Isasi
, Vivien Leung
, Judith Wylie-Rosett

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Purpose The purpose of the study was to examine the impact of a 12-month weight loss intervention with either a low-carbohydrate or a low-fat diet on quality of life (QOL) among obese patients with type 2 diabetes. Methods Participants were enrolled in a randomized trial comparing a low-carbohydrate to a low-fat diet in type 2 diabetes. QOL was assessed with the Diabetes-39 questionnaire, which measures QOL within 5 distinct scales: anxiety and worry, diabetes control, energy and mobility, social burden, and sexual functioning. Repeated measures ANOVA compared change in QOL scales at baseline and 6 and 12 months. Results Forty-six participants completed all measures. Following 12 months, there was a significant reduction in the scores related to sexual function and energy and mobility, suggesting improvement in QOL related to these domains. These changes were not significantly different between dietary arms. Changes in weight, A1C, and dietary composition were not significantly correlated with changes in QOL. Conclusions Participants with diabetes have various options for weight loss. Dietary interventions with either low-carbohydrate or low-fat diets may lead to some improvements in QOL in patients with type 2 diabetes.

Original language	English
Pages (from-to)	250-255
Number of pages	6
Journal	Science of Diabetes Self-Management and Care
Volume	38
Issue number	2
DOIs	https://doi.org/10.1177/0145721711436132
State	Published - Mar 2012
Externally published	Yes

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10.1177/0145721711436132

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@article{6083437ad1314f029ce1c100ff006f22,

title = "Diabetes-specific Quality of Life After a Low-carbohydrate and Low-fat Dietary Intervention",

abstract = "Purpose The purpose of the study was to examine the impact of a 12-month weight loss intervention with either a low-carbohydrate or a low-fat diet on quality of life (QOL) among obese patients with type 2 diabetes. Methods Participants were enrolled in a randomized trial comparing a low-carbohydrate to a low-fat diet in type 2 diabetes. QOL was assessed with the Diabetes-39 questionnaire, which measures QOL within 5 distinct scales: anxiety and worry, diabetes control, energy and mobility, social burden, and sexual functioning. Repeated measures ANOVA compared change in QOL scales at baseline and 6 and 12 months. Results Forty-six participants completed all measures. Following 12 months, there was a significant reduction in the scores related to sexual function and energy and mobility, suggesting improvement in QOL related to these domains. These changes were not significantly different between dietary arms. Changes in weight, A1C, and dietary composition were not significantly correlated with changes in QOL. Conclusions Participants with diabetes have various options for weight loss. Dietary interventions with either low-carbohydrate or low-fat diets may lead to some improvements in QOL in patients with type 2 diabetes.",

author = "Davis, \{Nichola J.\} and Nora Tomuta and Isasi, \{Carmen R.\} and Vivien Leung and Judith Wylie-Rosett",

note = "Funding Information: This research was supported by the Robert C. and Veronica Atkins Foundation, awarded to Dr Wylie-Rosett, the Diabetes Research and Training Center (P60 DK020541), and the Clinical and Translational Science Award (UL1 RR025750) Clinicaltrials.gov registration: NCT00795691.",

year = "2012",

month = mar,

doi = "10.1177/0145721711436132",

language = "English",

volume = "38",

pages = "250--255",

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T1 - Diabetes-specific Quality of Life After a Low-carbohydrate and Low-fat Dietary Intervention

AU - Davis, Nichola J.

AU - Tomuta, Nora

AU - Isasi, Carmen R.

AU - Leung, Vivien

AU - Wylie-Rosett, Judith

N1 - Funding Information: This research was supported by the Robert C. and Veronica Atkins Foundation, awarded to Dr Wylie-Rosett, the Diabetes Research and Training Center (P60 DK020541), and the Clinical and Translational Science Award (UL1 RR025750) Clinicaltrials.gov registration: NCT00795691.

PY - 2012/3

Y1 - 2012/3

N2 - Purpose The purpose of the study was to examine the impact of a 12-month weight loss intervention with either a low-carbohydrate or a low-fat diet on quality of life (QOL) among obese patients with type 2 diabetes. Methods Participants were enrolled in a randomized trial comparing a low-carbohydrate to a low-fat diet in type 2 diabetes. QOL was assessed with the Diabetes-39 questionnaire, which measures QOL within 5 distinct scales: anxiety and worry, diabetes control, energy and mobility, social burden, and sexual functioning. Repeated measures ANOVA compared change in QOL scales at baseline and 6 and 12 months. Results Forty-six participants completed all measures. Following 12 months, there was a significant reduction in the scores related to sexual function and energy and mobility, suggesting improvement in QOL related to these domains. These changes were not significantly different between dietary arms. Changes in weight, A1C, and dietary composition were not significantly correlated with changes in QOL. Conclusions Participants with diabetes have various options for weight loss. Dietary interventions with either low-carbohydrate or low-fat diets may lead to some improvements in QOL in patients with type 2 diabetes.

AB - Purpose The purpose of the study was to examine the impact of a 12-month weight loss intervention with either a low-carbohydrate or a low-fat diet on quality of life (QOL) among obese patients with type 2 diabetes. Methods Participants were enrolled in a randomized trial comparing a low-carbohydrate to a low-fat diet in type 2 diabetes. QOL was assessed with the Diabetes-39 questionnaire, which measures QOL within 5 distinct scales: anxiety and worry, diabetes control, energy and mobility, social burden, and sexual functioning. Repeated measures ANOVA compared change in QOL scales at baseline and 6 and 12 months. Results Forty-six participants completed all measures. Following 12 months, there was a significant reduction in the scores related to sexual function and energy and mobility, suggesting improvement in QOL related to these domains. These changes were not significantly different between dietary arms. Changes in weight, A1C, and dietary composition were not significantly correlated with changes in QOL. Conclusions Participants with diabetes have various options for weight loss. Dietary interventions with either low-carbohydrate or low-fat diets may lead to some improvements in QOL in patients with type 2 diabetes.

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JO - Science of Diabetes Self-Management and Care

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Diabetes-specific Quality of Life After a Low-carbohydrate and Low-fat Dietary Intervention

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