Diabetes-specific nutrition formulas in the management of patients with diabetes and cardiometabolic risk

Jeffrey I. Mechanick, Albert Marchetti, Refaat Hegazi, Osama Hamdy

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


Food-based dietary management, enhanced with evidence-based commercial products, such as diabetes-specific nutrition formulas (DSNFs), can help control the development, progression, and severity of certain chronic diseases. In this review, evidence is detailed on the use of DSNFs in patients with or at risk for diabetes and cardiometabolic-based chronic disease. Many DSNF strategies target glycemic excursions and cardiovascular physiology, taking into account various elements of healthy eating patterns. Nevertheless, significant research, knowledge, and practice gaps remain. These gaps are actionable in terms of formulating and testing relevant and pragmatic research questions, developing an educational program for the uniform distribution of information, and collaboratively writing clinical practice guidelines that incorporate the evidence base for DSNF. In sum, the benefits of DNSF as part of validated clinical practice algorithms include mitigation of chronic disease progression, cost-savings for the healthcare system, and applicability on a global scale.

Original languageEnglish
Article number3616
Pages (from-to)1-16
Number of pages16
Issue number12
StatePublished - Dec 2020


  • Adiposity
  • Cardiometabolic
  • Cardiovascular
  • Diabetes
  • Diabetes-specific nutrition formula
  • Dysglycemia
  • Dyslipidemia
  • Nutrition
  • Therapy
  • Type 2 diabetes


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