Devilish Effects of Taz in Nonalcoholic Steatohepatitis

Scott L. Friedman; Youngmin A. Lee

doi:10.1016/j.cmet.2016.10.006

Devilish Effects of Taz in Nonalcoholic Steatohepatitis

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

Nonalcoholic steatohepatitis leads to cirrhosis and cancer in a rising number of patients with metabolic syndrome. In this issue of Cell Metabolism, Wang et al. (2016) identify the transcriptional co-activator Taz as a driver of inflammation and fibrosis through the induction of Indian hedgehog in hepatocytes, which stimulates fibrogenesis by hepatic stellate cells.

Original language	English
Pages (from-to)	771-772
Number of pages	2
Journal	Cell Metabolism
Volume	24
Issue number	6
DOIs	https://doi.org/10.1016/j.cmet.2016.10.006
State	Published - 13 Dec 2016

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@article{b0520427ad52406aa1f83282821ad050,

title = "Devilish Effects of Taz in Nonalcoholic Steatohepatitis",

abstract = "Nonalcoholic steatohepatitis leads to cirrhosis and cancer in a rising number of patients with metabolic syndrome. In this issue of Cell Metabolism, Wang et al. (2016) identify the transcriptional co-activator Taz as a driver of inflammation and fibrosis through the induction of Indian hedgehog in hepatocytes, which stimulates fibrogenesis by hepatic stellate cells.",

author = "Friedman, \{Scott L.\} and Lee, \{Youngmin A.\}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = dec,

day = "13",

doi = "10.1016/j.cmet.2016.10.006",

language = "English",

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journal = "Cell Metabolism",

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TY - JOUR

T1 - Devilish Effects of Taz in Nonalcoholic Steatohepatitis

AU - Friedman, Scott L.

AU - Lee, Youngmin A.

PY - 2016/12/13

Y1 - 2016/12/13

N2 - Nonalcoholic steatohepatitis leads to cirrhosis and cancer in a rising number of patients with metabolic syndrome. In this issue of Cell Metabolism, Wang et al. (2016) identify the transcriptional co-activator Taz as a driver of inflammation and fibrosis through the induction of Indian hedgehog in hepatocytes, which stimulates fibrogenesis by hepatic stellate cells.

AB - Nonalcoholic steatohepatitis leads to cirrhosis and cancer in a rising number of patients with metabolic syndrome. In this issue of Cell Metabolism, Wang et al. (2016) identify the transcriptional co-activator Taz as a driver of inflammation and fibrosis through the induction of Indian hedgehog in hepatocytes, which stimulates fibrogenesis by hepatic stellate cells.

UR - https://www.scopus.com/pages/publications/85003848875

U2 - 10.1016/j.cmet.2016.10.006

DO - 10.1016/j.cmet.2016.10.006

M3 - Short survey

C2 - 28068221

AN - SCOPUS:85003848875

SN - 1550-4131

VL - 24

SP - 771

EP - 772

JO - Cell Metabolism

JF - Cell Metabolism

IS - 6

ER -

Devilish Effects of Taz in Nonalcoholic Steatohepatitis

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