Devilish Effects of Taz in Nonalcoholic Steatohepatitis

Scott L. Friedman; Youngmin A. Lee

doi:10.1016/j.cmet.2016.10.006

Devilish Effects of Taz in Nonalcoholic Steatohepatitis

Scott L. Friedman, Youngmin A. Lee

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Nonalcoholic steatohepatitis leads to cirrhosis and cancer in a rising number of patients with metabolic syndrome. In this issue of Cell Metabolism, Wang et al. (2016) identify the transcriptional co-activator Taz as a driver of inflammation and fibrosis through the induction of Indian hedgehog in hepatocytes, which stimulates fibrogenesis by hepatic stellate cells.

Original language	English
Pages (from-to)	771-772
Number of pages	2
Journal	Cell Metabolism
Volume	24
Issue number	6
DOIs	https://doi.org/10.1016/j.cmet.2016.10.006
State	Published - 13 Dec 2016

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title = "Devilish Effects of Taz in Nonalcoholic Steatohepatitis",

abstract = "Nonalcoholic steatohepatitis leads to cirrhosis and cancer in a rising number of patients with metabolic syndrome. In this issue of Cell Metabolism, Wang et al. (2016) identify the transcriptional co-activator Taz as a driver of inflammation and fibrosis through the induction of Indian hedgehog in hepatocytes, which stimulates fibrogenesis by hepatic stellate cells.",

author = "Friedman, {Scott L.} and Lee, {Youngmin A.}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = dec,

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language = "English",

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T1 - Devilish Effects of Taz in Nonalcoholic Steatohepatitis

AU - Friedman, Scott L.

AU - Lee, Youngmin A.

PY - 2016/12/13

Y1 - 2016/12/13

N2 - Nonalcoholic steatohepatitis leads to cirrhosis and cancer in a rising number of patients with metabolic syndrome. In this issue of Cell Metabolism, Wang et al. (2016) identify the transcriptional co-activator Taz as a driver of inflammation and fibrosis through the induction of Indian hedgehog in hepatocytes, which stimulates fibrogenesis by hepatic stellate cells.

AB - Nonalcoholic steatohepatitis leads to cirrhosis and cancer in a rising number of patients with metabolic syndrome. In this issue of Cell Metabolism, Wang et al. (2016) identify the transcriptional co-activator Taz as a driver of inflammation and fibrosis through the induction of Indian hedgehog in hepatocytes, which stimulates fibrogenesis by hepatic stellate cells.

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U2 - 10.1016/j.cmet.2016.10.006

DO - 10.1016/j.cmet.2016.10.006

M3 - Short survey

C2 - 28068221

AN - SCOPUS:85003848875

SN - 1550-4131

VL - 24

SP - 771

EP - 772

JO - Cell Metabolism

JF - Cell Metabolism

IS - 6

ER -

Devilish Effects of Taz in Nonalcoholic Steatohepatitis

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