Development of Pharmaceutically Adapted Mesoporous Silica Nanoparticles for siRNA Delivery

Wilson X. Mai; Tian Xia; Huan Meng

doi:10.1002/9781118610749.ch9

Development of Pharmaceutically Adapted Mesoporous Silica Nanoparticles for siRNA Delivery

Wilson X. Mai
, Tian Xia
, Huan Meng

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

Mesoporous silica nanoparticle (MSNP) is a multifunctional inorganic nanomaterial platform that offers a novel approach for siRNA delivery. It combines the robustness of the inorganic system with the ability of imaging, on-demand cargo release, and targeting. This chapter discusses the synthesis, surface modification, and applications of MSNP for siRNA delivery.

Original language	English
Title of host publication	Advanced Delivery and Therapeutic Applications of RNAi
Publisher	John Wiley and Sons
Pages	187-205
Number of pages	19
ISBN (Print)	9781119976868
DOIs	https://doi.org/10.1002/9781118610749.ch9
State	Published - 26 Apr 2013
Externally published	Yes

Keywords

Inorganic nanocarrier
Mesoporous silica nanoparticle (MSNP)
SiRNA delivery
Surface modification

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10.1002/9781118610749.ch9

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title = "Development of Pharmaceutically Adapted Mesoporous Silica Nanoparticles for siRNA Delivery",

abstract = "Mesoporous silica nanoparticle (MSNP) is a multifunctional inorganic nanomaterial platform that offers a novel approach for siRNA delivery. It combines the robustness of the inorganic system with the ability of imaging, on-demand cargo release, and targeting. This chapter discusses the synthesis, surface modification, and applications of MSNP for siRNA delivery.",

keywords = "Inorganic nanocarrier, Mesoporous silica nanoparticle (MSNP), SiRNA delivery, Surface modification",

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AU - Xia, Tian

AU - Meng, Huan

PY - 2013/4/26

Y1 - 2013/4/26

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AB - Mesoporous silica nanoparticle (MSNP) is a multifunctional inorganic nanomaterial platform that offers a novel approach for siRNA delivery. It combines the robustness of the inorganic system with the ability of imaging, on-demand cargo release, and targeting. This chapter discusses the synthesis, surface modification, and applications of MSNP for siRNA delivery.

KW - Inorganic nanocarrier

KW - Mesoporous silica nanoparticle (MSNP)

KW - SiRNA delivery

KW - Surface modification

UR - https://www.scopus.com/pages/publications/84887210074

U2 - 10.1002/9781118610749.ch9

DO - 10.1002/9781118610749.ch9

M3 - Chapter

AN - SCOPUS:84887210074

SN - 9781119976868

SP - 187

EP - 205

BT - Advanced Delivery and Therapeutic Applications of RNAi

PB - John Wiley and Sons

ER -

Development of Pharmaceutically Adapted Mesoporous Silica Nanoparticles for siRNA Delivery

Abstract

Keywords

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