Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

F. G.R. Fowkes; G. D. Murray; I. Butcher; A. R. Folsom; A. T. Hirsch; D. J. Couper; G. Debacker; M. Kornitzer; A. B. Newman; K. C. Sutton-Tyrrell; M. Cushman; A. J. Lee; J. F. Price; R. B. D'Agostino; J. M. Murabito; P. E. Norman; K. H. Masaki; L. M. Bouter; R. J. Heine; C. D.A. Stehouwer; M. M. McDermott; H. E.J.H. Stoffers; J. A. Knottnerus; M. Ogren; B. Hedblad; W. Koenig; C. Meisinger; J. A. Cauley; O. H. Franco; M. G.M. Hunink; A. Hofman; J. C. Witteman; M. H. Criqui; R. D. Langer; W. R. Hiatt; R. F. Hamman

doi:10.1177/2047487313516564

Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

F. G.R. Fowkes
, G. D. Murray
, I. Butcher
, A. R. Folsom
, A. T. Hirsch
, D. J. Couper
, G. Debacker
, M. Kornitzer
, A. B. Newman
, K. C. Sutton-Tyrrell
, M. Cushman
, A. J. Lee
, J. F. Price
, R. B. D'Agostino
, J. M. Murabito
, P. E. Norman
, K. H. Masaki
, L. M. Bouter
, R. J. Heine
, C. D.A. Stehouwer

M. M. McDermott, H. E.J.H. Stoffers, J. A. Knottnerus, M. Ogren, B. Hedblad, W. Koenig, C. Meisinger, J. A. Cauley, O. H. Franco, M. G.M. Hunink, A. Hofman, J. C. Witteman, M. H. Criqui, R. D. Langer, W. R. Hiatt, R. F. Hamman

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events.

Original language	English
Pages (from-to)	310-320
Number of pages	11
Journal	European Journal of Preventive Cardiology
Volume	21
Issue number	3
DOIs	https://doi.org/10.1177/2047487313516564
State	Published - Mar 2014
Externally published	Yes

Keywords

Ankle brachial index
cardiovascular diseases
risk assessment

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10.1177/2047487313516564

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Fowkes, F. G. R., Murray, G. D., Butcher, I., Folsom, A. R., Hirsch, A. T., Couper, D. J., Debacker, G., Kornitzer, M., Newman, A. B., Sutton-Tyrrell, K. C., Cushman, M., Lee, A. J., Price, J. F., D'Agostino, R. B., Murabito, J. M., Norman, P. E., Masaki, K. H., Bouter, L. M., Heine, R. J., ... Hamman, R. F. (2014). Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events. European Journal of Preventive Cardiology, 21(3), 310-320. https://doi.org/10.1177/2047487313516564

@article{3a177cc239c04f2dab39b9dbf2232ba3,

title = "Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events",

abstract = "Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events.",

keywords = "Ankle brachial index, cardiovascular diseases, risk assessment",

author = "Fowkes, \{F. G.R.\} and Murray, \{G. D.\} and I. Butcher and Folsom, \{A. R.\} and Hirsch, \{A. T.\} and Couper, \{D. J.\} and G. Debacker and M. Kornitzer and Newman, \{A. B.\} and Sutton-Tyrrell, \{K. C.\} and M. Cushman and Lee, \{A. J.\} and Price, \{J. F.\} and D'Agostino, \{R. B.\} and Murabito, \{J. M.\} and Norman, \{P. E.\} and Masaki, \{K. H.\} and Bouter, \{L. M.\} and Heine, \{R. J.\} and Stehouwer, \{C. D.A.\} and McDermott, \{M. M.\} and Stoffers, \{H. E.J.H.\} and Knottnerus, \{J. A.\} and M. Ogren and B. Hedblad and W. Koenig and C. Meisinger and Cauley, \{J. A.\} and Franco, \{O. H.\} and Hunink, \{M. G.M.\} and A. Hofman and Witteman, \{J. C.\} and Criqui, \{M. H.\} and Langer, \{R. D.\} and Hiatt, \{W. R.\} and Hamman, \{R. F.\}",

note = "Funding Information: The ARIC study was supported by the National Heart, Lung, and Blood Institute (contracts HHSN268201100005C, -06C, -07C, -08C, -09C, -10C, -11C, and -12C).",

year = "2014",

month = mar,

doi = "10.1177/2047487313516564",

language = "English",

volume = "21",

pages = "310--320",

journal = "European Journal of Preventive Cardiology",

issn = "2047-4873",

publisher = "Oxford University Press",

number = "3",

}

Fowkes, FGR, Murray, GD, Butcher, I, Folsom, AR, Hirsch, AT, Couper, DJ, Debacker, G, Kornitzer, M, Newman, AB, Sutton-Tyrrell, KC, Cushman, M, Lee, AJ, Price, JF, D'Agostino, RB, Murabito, JM, Norman, PE, Masaki, KH, Bouter, LM, Heine, RJ, Stehouwer, CDA, McDermott, MM, Stoffers, HEJH, Knottnerus, JA, Ogren, M, Hedblad, B, Koenig, W, Meisinger, C, Cauley, JA, Franco, OH, Hunink, MGM, Hofman, A, Witteman, JC, Criqui, MH, Langer, RD, Hiatt, WR & Hamman, RF 2014, 'Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events', European Journal of Preventive Cardiology, vol. 21, no. 3, pp. 310-320. https://doi.org/10.1177/2047487313516564

TY - JOUR

T1 - Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

AU - Fowkes, F. G.R.

AU - Murray, G. D.

AU - Butcher, I.

AU - Folsom, A. R.

AU - Hirsch, A. T.

AU - Couper, D. J.

AU - Debacker, G.

AU - Kornitzer, M.

AU - Newman, A. B.

AU - Sutton-Tyrrell, K. C.

AU - Cushman, M.

AU - Lee, A. J.

AU - Price, J. F.

AU - D'Agostino, R. B.

AU - Murabito, J. M.

AU - Norman, P. E.

AU - Masaki, K. H.

AU - Bouter, L. M.

AU - Heine, R. J.

AU - Stehouwer, C. D.A.

AU - McDermott, M. M.

AU - Stoffers, H. E.J.H.

AU - Knottnerus, J. A.

AU - Ogren, M.

AU - Hedblad, B.

AU - Koenig, W.

AU - Meisinger, C.

AU - Cauley, J. A.

AU - Franco, O. H.

AU - Hunink, M. G.M.

AU - Hofman, A.

AU - Witteman, J. C.

AU - Criqui, M. H.

AU - Langer, R. D.

AU - Hiatt, W. R.

AU - Hamman, R. F.

N1 - Funding Information: The ARIC study was supported by the National Heart, Lung, and Blood Institute (contracts HHSN268201100005C, -06C, -07C, -08C, -09C, -10C, -11C, and -12C).

PY - 2014/3

Y1 - 2014/3

N2 - Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events.

AB - Background: The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design: An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods: Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS+ABI, were fitted for the primary outcome of major coronary events.

KW - Ankle brachial index

KW - cardiovascular diseases

KW - risk assessment

UR - https://www.scopus.com/pages/publications/84896697287

U2 - 10.1177/2047487313516564

DO - 10.1177/2047487313516564

M3 - Article

C2 - 24367001

AN - SCOPUS:84896697287

SN - 2047-4873

VL - 21

SP - 310

EP - 320

JO - European Journal of Preventive Cardiology

JF - European Journal of Preventive Cardiology

IS - 3

ER -

Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

Abstract

Keywords

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