TY - JOUR
T1 - Developing a consensus classification system for acute renal failure
AU - Kellum, John A.
AU - Levin, Nathan
AU - Bouman, Catherine
AU - Lameire, Norbert
PY - 2002/12
Y1 - 2002/12
N2 - A biochemical definition and classification system for acute renal dysfunction is long overdue. Its absence has impeded progress in clinical and even basic research concerning a syndrome associated with mortality rates of 30 to 80%. No definition of acute renal dysfunction will be perfect, but the absence of a definition or, worse, more than 35 separate definitions, as found in the literature, is unacceptable. Many of the challenges, considerations, and controversies associated with achieving consensus and developing a classification for acute renal dysfunction are addressed. Recommendations for validating a classification system are also considered.
AB - A biochemical definition and classification system for acute renal dysfunction is long overdue. Its absence has impeded progress in clinical and even basic research concerning a syndrome associated with mortality rates of 30 to 80%. No definition of acute renal dysfunction will be perfect, but the absence of a definition or, worse, more than 35 separate definitions, as found in the literature, is unacceptable. Many of the challenges, considerations, and controversies associated with achieving consensus and developing a classification for acute renal dysfunction are addressed. Recommendations for validating a classification system are also considered.
UR - http://www.scopus.com/inward/record.url?scp=0036892434&partnerID=8YFLogxK
U2 - 10.1097/00075198-200212000-00005
DO - 10.1097/00075198-200212000-00005
M3 - Article
C2 - 12454534
AN - SCOPUS:0036892434
SN - 1070-5295
VL - 8
SP - 509
EP - 514
JO - Current Opinion in Critical Care
JF - Current Opinion in Critical Care
IS - 6
ER -