Determination of the regional function of the heart

Evren U. Azeloglu, Glenn R. Gaudette, Irvin B. Krukenkamp, Fu Pen Chiang

Research output: Contribution to journalConference articlepeer-review


Unlike many other engineering designs, the heart, a pressure vessel, shows variations within its chambers and surface in terms of mechanical function. This necessitates a whole field technique with high spatial resolution. Computer aided speckle interferometry (CASI), a nondestructive examination technique, is herein developed for this purpose. A speckle pattern was created on the surface of isolated rabbit hearts. Images of the beating hearts were acquired with a charge-couple device (CCD) camera for one second at a rate of 50 flames per second. CASI was used to determine the 2-D displacement vectors over regions of approximately 4 × 6 mm. Regional area stroke work (the integral of the left ventricular pressure with respect to area), the first invariant of the 2-D strain tensor, and the principle strains were used to determine the regional function. After occluding the blood supply to a region of the heart, significant changes were detected in all the previously mentioned parameters. Commonly used techniques cannot determine 2-D strain and lack the high spatial resolution of CASI. Determination of the 2-D strain can provide useful data on the functionality of the heart.

Original languageEnglish
Pages (from-to)137-145
Number of pages9
JournalAmerican Society of Mechanical Engineers, Pressure Vessels and Piping Division (Publication) PVP
StatePublished - 2002
Externally publishedYes
EventPiping and Component Analysis and Diagnostics -2002- (2002 ASME Prssure Vessels and Piping Conference) - Vancouver, BC, Canada
Duration: 5 Aug 20029 Aug 2002


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