Determinants of Seattle Angina Questionnaire in Multivessel Disease Patients Undergoing Percutaneous Coronary Intervention: Insights from a Single-Center Study

Suvruta Iruvanti, Amit Blumfield, Serdar Farhan, Clayton Snyder, Gurpreet Johal, Samantha Sartori, Birgit Vogel, Gennaro Giustino, Parasuram Melarcode-Krishnamoorthy, Htoo Kyaw, George Dangas, Roxana Mehran, Annapoorna Kini, Samin K. Sharma

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: The Seattle Angina Questionnaire (SAQ-7) quantifies the impact of angina on patient functionality and quality of life. There is scarce data on the impact of social determinants and comorbidities on SAQ-7 in patients undergoing percutaneous coronary intervention (PCI) with planned staged PCI. Methods: Patients completed a SAQ-7 before each PCI. Multivariable regression analysis was performed to study the impact of social determinants, comorbidities, and procedural characteristics on SAQ-7 scores at index PCI and at the time of the staged PCI. Results: 531 patients were studied. Female sex, non-White race, coronary artery bypass graft history (CABG), and chronic lung disease were associated with lower baseline SAQ-7 scores. Overall, SAQ-7 increased between index procedure and staged PCI (11.9 ± 23.4). Body mass index (BMI) and the treatment of bifurcation lesions were independently associated with improvement of SAQ-7 between PCIs. Post-intervention, neither sex nor race was independently associated with changes in SAQ-7 scores. Conclusion: Different disparities and comorbid factors affect SAQ-7 before and after PCI. After revascularization, sex and race were not independent predictors of SAQ-7 improvement.

Original languageEnglish
Pages (from-to)28-33
Number of pages6
JournalCardiovascular Revascularization Medicine
Volume49
DOIs
StatePublished - Apr 2023

Keywords

  • Comorbidities
  • SAQ
  • Social determinants

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