TY - JOUR
T1 - Determinants of Seattle Angina Questionnaire in Multivessel Disease Patients Undergoing Percutaneous Coronary Intervention
T2 - Insights from a Single-Center Study
AU - Iruvanti, Suvruta
AU - Blumfield, Amit
AU - Farhan, Serdar
AU - Snyder, Clayton
AU - Johal, Gurpreet
AU - Sartori, Samantha
AU - Vogel, Birgit
AU - Giustino, Gennaro
AU - Melarcode-Krishnamoorthy, Parasuram
AU - Kyaw, Htoo
AU - Dangas, George
AU - Mehran, Roxana
AU - Kini, Annapoorna
AU - Sharma, Samin K.
N1 - Publisher Copyright:
© 2023 Elsevier Inc.
PY - 2023
Y1 - 2023
N2 - Introduction: The Seattle Angina Questionnaire (SAQ-7) quantifies the impact of angina on patient functionality and quality of life. There is scarce data on the impact of social determinants and comorbidities on SAQ-7 in patients undergoing percutaneous coronary intervention (PCI) with planned staged PCI. Methods: Patients completed a SAQ-7 before each PCI. Multivariable regression analysis was performed to study the impact of social determinants, comorbidities, and procedural characteristics on SAQ-7 scores at index PCI and at the time of the staged PCI. Results: 531 patients were studied. Female sex, non-White race, coronary artery bypass graft history (CABG), and chronic lung disease were associated with lower baseline SAQ-7 scores. Overall, SAQ-7 increased between index procedure and staged PCI (11.9 ± 23.4). Body mass index (BMI) and the treatment of bifurcation lesions were independently associated with improvement of SAQ-7 between PCIs. Post-intervention, neither sex nor race was independently associated with changes in SAQ-7 scores. Conclusion: Different disparities and comorbid factors affect SAQ-7 before and after PCI. After revascularization, sex and race were not independent predictors of SAQ-7 improvement.
AB - Introduction: The Seattle Angina Questionnaire (SAQ-7) quantifies the impact of angina on patient functionality and quality of life. There is scarce data on the impact of social determinants and comorbidities on SAQ-7 in patients undergoing percutaneous coronary intervention (PCI) with planned staged PCI. Methods: Patients completed a SAQ-7 before each PCI. Multivariable regression analysis was performed to study the impact of social determinants, comorbidities, and procedural characteristics on SAQ-7 scores at index PCI and at the time of the staged PCI. Results: 531 patients were studied. Female sex, non-White race, coronary artery bypass graft history (CABG), and chronic lung disease were associated with lower baseline SAQ-7 scores. Overall, SAQ-7 increased between index procedure and staged PCI (11.9 ± 23.4). Body mass index (BMI) and the treatment of bifurcation lesions were independently associated with improvement of SAQ-7 between PCIs. Post-intervention, neither sex nor race was independently associated with changes in SAQ-7 scores. Conclusion: Different disparities and comorbid factors affect SAQ-7 before and after PCI. After revascularization, sex and race were not independent predictors of SAQ-7 improvement.
KW - Comorbidities
KW - SAQ
KW - Social determinants
UR - http://www.scopus.com/inward/record.url?scp=85146022623&partnerID=8YFLogxK
U2 - 10.1016/j.carrev.2022.12.012
DO - 10.1016/j.carrev.2022.12.012
M3 - Article
C2 - 36624012
AN - SCOPUS:85146022623
SN - 1553-8389
VL - 49
SP - 28
EP - 33
JO - Cardiovascular Revascularization Medicine
JF - Cardiovascular Revascularization Medicine
ER -