TY - JOUR
T1 - Detection of mild cognitive impairment and early stage dementia with an audio-recorded cognitive scale
AU - Sewell, Margaret C.
AU - Luo, Xiaodong
AU - Neugroschl, Judith
AU - Sano, Mary
PY - 2013/8
Y1 - 2013/8
N2 - Background: Physicians often miss diagnosis of mild cognitive impairment (MCI) or early dementia and screening measures can be insensitive to very mild impairments. Other cognitive assessments may take too much time or be frustrating to seniors. This study examine. The ability of an audio-recorded scale, developed in Australia, to detect MCI or mild Alzheimer's disease (AD) and compared cognitive domain-specific performance o. The audio-recorded scale to in-person battery and common cognitive screens. Method: Seventy-six patients fro. The Mount Sinai Alzheimer's Disease Research Center were recruited. Patients were aged 75 years or older, with clinical diagnosis of AD or MCI (n = 51) or normal control (n = 25). Participants underwent in-person neuropsychological testing followed by testing wit. The audio-recorded cognitive screen (ARCS). Results: ARCS provided better discrimination between normal and impaired elderly individuals than eithe. The Mini-Mental State Examination o. The clock drawing test. The in-person battery and ARCS analogous variables were significantly correlated, most i. The 0.4 to 0.7 range, including verbal memory, executive function/attention, naming, and verbal fluency. The area unde. The curve generated fro. The receiver operating characteristic curves indicated high and equivalent discrimination for ARCS an. The in-person battery (0.972 vs. 0.988; p = 0.23). Conclusion: The ARCS demonstrated better discrimination between normal controls and those with mild deficits than typical screening measures. Performance on cognitive domains withi. The ARCS was well correlated wit. The in-person battery. Completion o. The ARCS was accomplished despite mild difficulty hearin. The instructions even in very elderly participants, indicating that it may be a useful measure in primary care settings.
AB - Background: Physicians often miss diagnosis of mild cognitive impairment (MCI) or early dementia and screening measures can be insensitive to very mild impairments. Other cognitive assessments may take too much time or be frustrating to seniors. This study examine. The ability of an audio-recorded scale, developed in Australia, to detect MCI or mild Alzheimer's disease (AD) and compared cognitive domain-specific performance o. The audio-recorded scale to in-person battery and common cognitive screens. Method: Seventy-six patients fro. The Mount Sinai Alzheimer's Disease Research Center were recruited. Patients were aged 75 years or older, with clinical diagnosis of AD or MCI (n = 51) or normal control (n = 25). Participants underwent in-person neuropsychological testing followed by testing wit. The audio-recorded cognitive screen (ARCS). Results: ARCS provided better discrimination between normal and impaired elderly individuals than eithe. The Mini-Mental State Examination o. The clock drawing test. The in-person battery and ARCS analogous variables were significantly correlated, most i. The 0.4 to 0.7 range, including verbal memory, executive function/attention, naming, and verbal fluency. The area unde. The curve generated fro. The receiver operating characteristic curves indicated high and equivalent discrimination for ARCS an. The in-person battery (0.972 vs. 0.988; p = 0.23). Conclusion: The ARCS demonstrated better discrimination between normal controls and those with mild deficits than typical screening measures. Performance on cognitive domains withi. The ARCS was well correlated wit. The in-person battery. Completion o. The ARCS was accomplished despite mild difficulty hearin. The instructions even in very elderly participants, indicating that it may be a useful measure in primary care settings.
KW - Alzheimer's disease
KW - Cognitive assessment
KW - Diagnostic accuracy
KW - MCI
UR - http://www.scopus.com/inward/record.url?scp=84880083205&partnerID=8YFLogxK
U2 - 10.1017/S1041610213000598
DO - 10.1017/S1041610213000598
M3 - Article
C2 - 23635663
AN - SCOPUS:84880083205
SN - 1041-6102
VL - 25
SP - 1325
EP - 1333
JO - International Psychogeriatrics
JF - International Psychogeriatrics
IS - 8
ER -