Detection and toxin typing of Clostridium perfringens in formalin-fixed, paraffin-embedded tissue samples by PCR

Josephine Wu, Wandi Zhang, Boxun Xie, Maoxin Wu, Xiaodi Tong, Jayant Kalpoe, David Zhang

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

Since current microbiology methods are not suitable to detect Clostridium perfringens in formalin-fixed, paraffin-embedded tissue samples, we developed a PCR assay to detect toxin-encoding genes and the 16S rRNA gene of C. perfringens. We successfully detected and genotyped C. perfringens in tissue sections from two autopsy cases.

Original languageEnglish
Pages (from-to)807-810
Number of pages4
JournalJournal of Clinical Microbiology
Volume47
Issue number3
DOIs
StatePublished - Mar 2009

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