Designer genes: Filling the gap in transplantation

Minnie M. Sarwal, Li Li

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

Accelerated evolution of the field of functional genomics has been greatly facilitated by high-throughput microarray-based gene function studies, relating to the parallel and serial expression measurements of genomes. Microarray experimentation is being applied for the study of basic research questions, drug target discovery, pharmacology, toxicogenomics, target selectivity, disease biomarker determination, development of prognostic tests, and disease subclass determination. This article will review the current applications of microarray technology in the field of organ transplantation and discuss the potential impact of this technology on transplantation medicine.

Original languageEnglish
Pages (from-to)1261-1272
Number of pages12
JournalTransplantation
Volume82
Issue number10
DOIs
StatePublished - Nov 2006
Externally publishedYes

Keywords

  • Genes
  • Genomics
  • Microarray
  • Rejection
  • Transplantation

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