Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold

Wenwen Zhang; Xiaobao Yang; Weidong Chen; Xiaoyong Xu; Lu Li; Hongbin Zhai; Zhong Li

doi:10.1021/jf902034z

Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold

Wenwen Zhang, Xiaobao Yang, Weidong Chen, Xiaoyong Xu, Lu Li, Hongbin Zhai, Zhong Li

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Novel neonicotinoid analogues bearing a 1,4-dihydropridine scaffold were designed and synthesized by multicomponent reactions (MCRs) to enhance π-π stacking. The synthesized compounds were identified by ¹H NMR, ¹³C NMR, high-resolution mass spectroscopy, and elemental analysis. Bioassay tests showed that some of them exhibited high insecticidal activities against pea aphid (Aphis craccivora).

Original language	English
Pages (from-to)	2741-2745
Number of pages	5
Journal	Journal of Agricultural and Food Chemistry
Volume	58
Issue number	5
DOIs	https://doi.org/10.1021/jf902034z
State	Published - 10 Mar 2010
Externally published	Yes

Keywords

1,4-dihydropridine
Biological activity
Mcrs

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10.1021/jf902034z

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abstract = "Novel neonicotinoid analogues bearing a 1,4-dihydropridine scaffold were designed and synthesized by multicomponent reactions (MCRs) to enhance π-π stacking. The synthesized compounds were identified by 1H NMR, 13C NMR, high-resolution mass spectroscopy, and elemental analysis. Bioassay tests showed that some of them exhibited high insecticidal activities against pea aphid (Aphis craccivora).",

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author = "Wenwen Zhang and Xiaobao Yang and Weidong Chen and Xiaoyong Xu and Lu Li and Hongbin Zhai and Zhong Li",

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T1 - Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold

AU - Zhang, Wenwen

AU - Yang, Xiaobao

AU - Chen, Weidong

AU - Xu, Xiaoyong

AU - Li, Lu

AU - Zhai, Hongbin

AU - Li, Zhong

PY - 2010/3/10

Y1 - 2010/3/10

N2 - Novel neonicotinoid analogues bearing a 1,4-dihydropridine scaffold were designed and synthesized by multicomponent reactions (MCRs) to enhance π-π stacking. The synthesized compounds were identified by 1H NMR, 13C NMR, high-resolution mass spectroscopy, and elemental analysis. Bioassay tests showed that some of them exhibited high insecticidal activities against pea aphid (Aphis craccivora).

AB - Novel neonicotinoid analogues bearing a 1,4-dihydropridine scaffold were designed and synthesized by multicomponent reactions (MCRs) to enhance π-π stacking. The synthesized compounds were identified by 1H NMR, 13C NMR, high-resolution mass spectroscopy, and elemental analysis. Bioassay tests showed that some of them exhibited high insecticidal activities against pea aphid (Aphis craccivora).

KW - 1,4-dihydropridine

KW - Biological activity

KW - Mcrs

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U2 - 10.1021/jf902034z

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M3 - Article

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JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

IS - 5

ER -

Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold

Abstract

Keywords

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