Design and construction of a cost effective headstage for simultaneous neural stimulation and recording in the water maze

Prasad R. Shirvalkar, Mathew L. Shapiro

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Headstage preamplifiers and source followers are commonly used to study neural activity in behavioral neurophysiology experiments. Available commercial products are often expensive, not easily customized, and not submersible. Here we describe a method to design and build a customized, integrated circuit headstage for simultaneous 4-channel neural recording and 2-channel simulation in awake, behaving animals. The headstage is designed using a free, commercially available CAD-type design package, and can be modified easily to accommodate different scales (e.g. to add channels). A customized printed circuit board is built using surface mount resistors, capacitors and operational amplifiers to construct the unity gain source follower circuit. The headstage is made water-proof with a combination of epoxy, parafilm and a synthetic rubber putty. We have successfully used this device to record local field potentials and stimulate different brain regions simultaneously via independent channels in rats swimming in a water maze. The total cost is < $30/unit and can be manufactured readily.

Original languageEnglish
Article numbere2155
JournalJournal of Visualized Experiments
Issue number44
DOIs
StatePublished - Oct 2010

Keywords

  • Brain
  • Issue 44
  • Local field potential
  • Neuroscience
  • Recording
  • Stimulation
  • Water maze

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