Descemet stripping endothelial keratoplasty in eyes with previous glaucoma surgery

Joann J. Kang, David C. Ritterband, Kevin Lai, Jeffrey M. Liebmann, John A. Seedor

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Purpose: To evaluate visual outcomes and complications after Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with previous glaucoma surgery. Methods: A retrospective chart review was conducted of 129 procedures in 102 eyes of 96 patients who underwent DSAEK and previous glaucoma surgery at New York Eye and Ear Infirmary of Mt Sinai. The mean length of follow-up was 29.1 ± 25.5 months. Patients with postoperative follow-up duration of less than 3 months were excluded from analysis. Intraoperative and postoperative complications, postoperative course, and visual outcomes were analyzed. Results: Graft dislocation occurred in 46 eyes (35.7%) and 38 eyes required repeat injection of air in the anterior chamber. Primary graft failure occurred in 3 eyes (2.3%), early graft failure in 20 eyes (15.5%), and secondary graft failure developed in 29 eyes (22.5%). There was a statistically significant increase in secondary graft failure in patients with previous aqueous shunt implantation compared with eyes with previous trabeculectomy (P 0.03). Escalation of glaucoma therapy was needed medically in 25 eyes (24.5%), and 8 eyes (7.8%) required additional surgical intervention. Conclusions: There is a significant incidence of graft dislocation and graft failure after DSAEK in eyes with previous glaucoma surgery. In particular, aqueous shunt surgery compared with trabeculectomy may decrease long-term graft survival, and close follow-up is warranted.

Original languageEnglish
Pages (from-to)1520-1525
Number of pages6
Issue number12
StatePublished - 30 Jun 2016
Externally publishedYes


  • glaucoma
  • graft dislocation
  • graft failure


Dive into the research topics of 'Descemet stripping endothelial keratoplasty in eyes with previous glaucoma surgery'. Together they form a unique fingerprint.

Cite this