Dermatosis papulosa nigra: a clinically and histopathologically distinct entity

Simon Arda Metin, Brian W. Lee, William Clark Lambert, Lawrence Charles Parish

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Dermatosis papulosa nigra was first described by Aldo Castellani (1874-1971) more than 90 years ago, and it has since been presumed to be a variant of seborrheic keratosis. Despite their morphologic similarities both macroscopically and microscopically, key differences have yet to be explained. These lesions also exhibit different demographics, with dermatosis papulosa nigra having a predilection for dark-skinned individuals and a female predominance. No studies to date have investigated this, but studies assessing the mechanisms of similar dermatologic conditions may yield significant clues. The additional impact of environmental factors may also be important, but much controversy exists. Further investigations into dermatosis papulosa nigra are necessary to determine its pathogenesis and whether it should be regarded as a distinct entity.

Original languageEnglish
Pages (from-to)491-496
Number of pages6
JournalClinics in Dermatology
Issue number5
StatePublished - 1 Sep 2017
Externally publishedYes


Dive into the research topics of 'Dermatosis papulosa nigra: a clinically and histopathologically distinct entity'. Together they form a unique fingerprint.

Cite this