TY - JOUR
T1 - Depression, neighborhood deprivation and risk of type 2 diabetes
AU - Mezuk, Briana
AU - Chaikiat, Åsa
AU - Li, Xinjun
AU - Sundquist, Jan
AU - Kendler, Kenneth S.
AU - Sundquist, Kristina
N1 - Funding Information:
This study was supported by the grants from the National Institutes of Health (DK8356430 and MH093642), the Swedish Research Council, and ALF project grant, Lund, Sweden. The funding agencies had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript. The researchers were independent of the funding agencies.
PY - 2013/9
Y1 - 2013/9
N2 - Neighborhood characteristics have been associated with both depression and diabetes, but to date little attention has been paid to whether the association between depression and diabetes varies across different types of neighborhoods. This prospective study examined the relationship between depression, neighborhood deprivation, and risk of type 2 diabetes among 336,340 adults from a national-representative sample of primary care centers in Sweden (2001-2007). Multi-level logistic regression models were used to assess associations between depression and risk of type 2 diabetes across affluent and deprived neighborhoods. After accounting for demographic, individual-level socioeconomic, and health characteristics, depression was significantly associated with risk of diabetes (odds ratio (OR): 1.10, 95% confidence interval (CI): 1.06-1.14), as was neighborhood deprivation (OR for high vs. low deprivation: 1.66, 95% CI: 1.22-1.34). The interaction term between depression and neighborhood deprivation was non-significant, indicating that the relationship between depression and diabetes risk is similar across levels of neighborhood socioeconomic deprivation.
AB - Neighborhood characteristics have been associated with both depression and diabetes, but to date little attention has been paid to whether the association between depression and diabetes varies across different types of neighborhoods. This prospective study examined the relationship between depression, neighborhood deprivation, and risk of type 2 diabetes among 336,340 adults from a national-representative sample of primary care centers in Sweden (2001-2007). Multi-level logistic regression models were used to assess associations between depression and risk of type 2 diabetes across affluent and deprived neighborhoods. After accounting for demographic, individual-level socioeconomic, and health characteristics, depression was significantly associated with risk of diabetes (odds ratio (OR): 1.10, 95% confidence interval (CI): 1.06-1.14), as was neighborhood deprivation (OR for high vs. low deprivation: 1.66, 95% CI: 1.22-1.34). The interaction term between depression and neighborhood deprivation was non-significant, indicating that the relationship between depression and diabetes risk is similar across levels of neighborhood socioeconomic deprivation.
KW - Depression
KW - Multi-level analysis
KW - Residence characteristics
KW - Socioeconomic factors
KW - Type 2 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=84879307599&partnerID=8YFLogxK
U2 - 10.1016/j.healthplace.2013.05.004
DO - 10.1016/j.healthplace.2013.05.004
M3 - Article
AN - SCOPUS:84879307599
SN - 1353-8292
VL - 23
SP - 63
EP - 69
JO - Health and Place
JF - Health and Place
ER -