Abstract
Interferon remains an essential component of treatment regimens for chronic hepatitis C infection. Mood disturbances, including depression, are relatively common in the hepatitis C virus-infected population and may worsen during hepatitis C treatment. Screening for depression prior to commencement of therapy is crucial and may improve treatment outcomes. Whether prophylactic antidepressant therapy should be initiated prior to therapy of hepatitis C virus infection with an interferon-based regimen remains unclear. We review the epidemiology, diagnosis, and management of depression before and during treatment of hepatitis C virus infection with interferon.
Original language | English |
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Pages (from-to) | 25-35 |
Number of pages | 11 |
Journal | International Journal of Interferon, Cytokine and Mediator Research |
Volume | 4 |
Issue number | 1 |
DOIs | |
State | Published - 27 Mar 2012 |
Externally published | Yes |
Keywords
- Cytokines
- Depression
- Hepatitis C
- Pegylated interferon
- Suicide risk