TY - JOUR
T1 - Depression - A common disorder across a broad spectrum of neurological conditions
T2 - A cross-sectional nationally representative survey
AU - Bulloch, Andrew G.M.
AU - Fiest, Kirsten M.
AU - Williams, Jeanne V.A.
AU - Lavorato, Dina H.
AU - Berzins, Sandra A.
AU - Jetté, Nathalie
AU - Pringsheim, Tamara M.
AU - Patten, Scott B.
N1 - Funding Information:
This project was supported by a grant from the Hotchkiss Brain Institute at the University of Calgary. This Institute had no role in study design, in the collection, analysis and interpretation of data, in the writing of the report or in the decision to submit the article for publication. Scott Patten, Nathalie Jette and Kirsten Fiest were supported by salary awards by Alberta Innovates — Health Solutions. Nathalie Jette also holds a Canada Research Chair Tier 2 in Neuroscience Health Services Research. Sandy Berzins was supported by an operating grant from the Alberta Addiction and Mental Health Research Partnership Program and by an endMS Studentship.
Publisher Copyright:
© 2015 Elsevier Inc. All rights reserved.
PY - 2015/11
Y1 - 2015/11
N2 - Objective: To estimate the prevalence of depression across a range of neurological conditions in a nationally representative sample. Methods: The data source was the Survey of Living with Neurological Conditions in Canada (SLNCC), which accrued its sample by selecting participants from the Canadian Community Health Survey. The point prevalence of depression was estimated by assessment of depressive symptoms with the Patient Health Questionnaire, Brief (Patient Health Questionnaire, 9-item). Results: A total of n=4408 participated in the SLNCC. The highest point prevalence of depression (> 30%) was seen in those with traumatic brain injury and brain/spinal cord tumors. Depression was also highly prevalent (18-28%) in those with (listed from highest to lowest) Alzheimer's disease/dementia, dystonia, multiple sclerosis, Parkinson's disease, stroke, migraine, epilepsy and spina bifida. The odds ratios for depression, with the referent group being the general population, were significant (from highest to lowest) for migraine, traumatic brain injury, stroke, dystonia and epilepsy. Conclusions: All neurological conditions included in this study are associated with an elevated prevalence of depression in community populations. The conditions with the highest prevalence are traumatic brain injury and brain/spinal cord tumors.
AB - Objective: To estimate the prevalence of depression across a range of neurological conditions in a nationally representative sample. Methods: The data source was the Survey of Living with Neurological Conditions in Canada (SLNCC), which accrued its sample by selecting participants from the Canadian Community Health Survey. The point prevalence of depression was estimated by assessment of depressive symptoms with the Patient Health Questionnaire, Brief (Patient Health Questionnaire, 9-item). Results: A total of n=4408 participated in the SLNCC. The highest point prevalence of depression (> 30%) was seen in those with traumatic brain injury and brain/spinal cord tumors. Depression was also highly prevalent (18-28%) in those with (listed from highest to lowest) Alzheimer's disease/dementia, dystonia, multiple sclerosis, Parkinson's disease, stroke, migraine, epilepsy and spina bifida. The odds ratios for depression, with the referent group being the general population, were significant (from highest to lowest) for migraine, traumatic brain injury, stroke, dystonia and epilepsy. Conclusions: All neurological conditions included in this study are associated with an elevated prevalence of depression in community populations. The conditions with the highest prevalence are traumatic brain injury and brain/spinal cord tumors.
KW - Community-based study
KW - Depression rating scales
KW - Depressive disorder
KW - Neurological conditions
KW - Prevalence
UR - http://www.scopus.com/inward/record.url?scp=84946479141&partnerID=8YFLogxK
U2 - 10.1016/j.genhosppsych.2015.06.007
DO - 10.1016/j.genhosppsych.2015.06.007
M3 - Article
C2 - 26153456
AN - SCOPUS:84946479141
SN - 0163-8343
VL - 37
SP - 507
EP - 512
JO - General Hospital Psychiatry
JF - General Hospital Psychiatry
IS - 6
ER -