TY - JOUR
T1 - Delusional and nondelusional unipolar depression
T2 - Further evidence for distinct subtypes
AU - Charney, D. S.
AU - Nelson, J. C.
PY - 1981
Y1 - 1981
N2 - In a retrospective analysis, the course, symptoms, treatment response, and personality of 54 delusional and 66 nondelusional unipolar depressed patients were compared. The delusional patients had more guilt feelings and were more ruminative, agitated, and referential than the nondelusional patients. They had a poor response to tricyclic antidepressant therapy but good treatment outcome with a tricyclic-antipsychotic combination or ECT. The form and content of prior episodes were remarkably similar to the index episode in both groups. The authors believe that these findings support the conception of unipolar delusional depression as a distinct subtype of depressive illness.
AB - In a retrospective analysis, the course, symptoms, treatment response, and personality of 54 delusional and 66 nondelusional unipolar depressed patients were compared. The delusional patients had more guilt feelings and were more ruminative, agitated, and referential than the nondelusional patients. They had a poor response to tricyclic antidepressant therapy but good treatment outcome with a tricyclic-antipsychotic combination or ECT. The form and content of prior episodes were remarkably similar to the index episode in both groups. The authors believe that these findings support the conception of unipolar delusional depression as a distinct subtype of depressive illness.
UR - http://www.scopus.com/inward/record.url?scp=0019468284&partnerID=8YFLogxK
U2 - 10.1176/ajp.138.3.328
DO - 10.1176/ajp.138.3.328
M3 - Article
C2 - 6110345
AN - SCOPUS:0019468284
SN - 0002-953X
VL - 138
SP - 328
EP - 333
JO - American Journal of Psychiatry
JF - American Journal of Psychiatry
IS - 3
ER -