Delayed-onset multifocal polymicrobial keratitis after laser in situ keratomileusis

David Ritterband, James Kelly, Tara McNamara, Michael Kresloff, Richard Koplin, John Seedor

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


We report a case of mixed Aspergillus fumigatus and coagulase-negative Staphylococcus stromal keratitis in a 43-year-old man who developed discomfort and swelling in his right eye 20 days after uneventful bilateral laser in situ keratomileusis (LASIK). Clinical examination revealed 2 distinct corneal infiltrates beneath the LASIK flap. Corneal scrapings were taken for microscopic examination and culture. Both infiltrates initially improved on topical antibiotic therapy, but over the next 18 days, 1 infiltrate worsened and repeat cultures were performed, which demonstrated A fumigatus. Natamycin 5% and amphotericin 0.1% were started and continued for 8 weeks with resolution of the infiltrate and return of the best corrected visual acuity. Delayed-onset multifocal keratitis is a rare complication of LASIK. Fungal entities should be considered in the differential diagnosis.

Original languageEnglish
Pages (from-to)898-899
Number of pages2
JournalJournal of Cataract and Refractive Surgery
Issue number5
StatePublished - 2002
Externally publishedYes


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