del(2)(p23): A new recurrent abnormality in acute myeloid leukemia

V. Najfeld, A. Scalise, S. Fruchtman, K. Troy

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

In two patients with acute myeloid leukemia, we found a new chromosome abnormality: del(2)(p23) which was detected in 13% and 50% of studied bone marrow cells, respectively. In patient one, del(2p) was an additional abnormality to t(8;21), while patient two had del(2p) as the sole abnormality. Based on our observation and a review of the literature we propose that del(2p) is a new recurrent chromosome abnormality for acute myeloid leukemia.

Original languageEnglish
Pages (from-to)185-190
Number of pages6
JournalCancer Genetics and Cytogenetics
Volume46
Issue number2
DOIs
StatePublished - Jun 1990

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