Defensins in viral infection

  • Rachna Shah
  • , Theresa L. Chang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

8 Scopus citations

Abstract

Defensins are antimicrobial peptides important for innate immune responses. Defensins can positively or negatively modulate infection by both enveloped and non-enveloped viruses. The effect of defensins on viral infection varies significantly depending on the specific virus, defensin and cell type in vitro. This chapter focuses on the interplay between human defensins and viral infection. Understanding the functions of defensins in viral infection may provide insights into developing novel anti-viral preventative or therapeutic strategies.

Original languageEnglish
Title of host publicationSmall Wonders
Subtitle of host publicationPeptides for Disease Control
PublisherAmerican Chemical Society
Pages137-171
Number of pages35
ISBN (Print)9780841227484
DOIs
StatePublished - 2012
Externally publishedYes

Publication series

NameACS Symposium Series
Volume1095
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

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