Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression

  • Richard Gorlick
  • , Erdem Goker
  • , Tanya Trippett
  • , Peter Steinherz
  • , Yaroslav Elisseyeff
  • , Madhu Mazumdar
  • , Wayne F. Flintoff
  • , Joseph R. Bertino

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171 Scopus citations

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Medicine and Dentistry

Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology

Neuroscience

Immunology and Microbiology