Deep Brain Stimulation of the Pallidofugal Pathways to Rescue Severe Life-Threatening Dyskinesias after STN-DBS Lead Implantation

Josue M. Avecillas-Chasin; Joohi Jimenez-Shahed; Joan Miravite; Susan Bressman; Brian H. Kopell

doi:10.1159/000519578

Deep Brain Stimulation of the Pallidofugal Pathways to Rescue Severe Life-Threatening Dyskinesias after STN-DBS Lead Implantation

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6 Scopus citations

Abstract

We present a patient with severe life-threatening dyskinesias due to a persistent microlesion effect after STN-DBS electrode implantation. The pallidofugal pathways were identified using patient-specific tractography, and steering the current toward this white matter structure resulted in complete resolution of the severe dyskinesias.

Original language	English
Pages (from-to)	95-98
Number of pages	4
Journal	Stereotactic and Functional Neurosurgery
Volume	100
Issue number	2
DOIs	https://doi.org/10.1159/000519578
State	Published - 1 Mar 2022

Keywords

Deep brain stimulation
Dyskinesias
Movement disorder
Neuromodulation
Parkinson
Tractography
White matter

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10.1159/000519578

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title = "Deep Brain Stimulation of the Pallidofugal Pathways to Rescue Severe Life-Threatening Dyskinesias after STN-DBS Lead Implantation",

abstract = "We present a patient with severe life-threatening dyskinesias due to a persistent microlesion effect after STN-DBS electrode implantation. The pallidofugal pathways were identified using patient-specific tractography, and steering the current toward this white matter structure resulted in complete resolution of the severe dyskinesias.",

keywords = "Deep brain stimulation, Dyskinesias, Movement disorder, Neuromodulation, Parkinson, Tractography, White matter",

author = "Avecillas-Chasin, \{Josue M.\} and Joohi Jimenez-Shahed and Joan Miravite and Susan Bressman and Kopell, \{Brian H.\}",

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AU - Avecillas-Chasin, Josue M.

AU - Jimenez-Shahed, Joohi

AU - Miravite, Joan

AU - Bressman, Susan

AU - Kopell, Brian H.

PY - 2022/3/1

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AB - We present a patient with severe life-threatening dyskinesias due to a persistent microlesion effect after STN-DBS electrode implantation. The pallidofugal pathways were identified using patient-specific tractography, and steering the current toward this white matter structure resulted in complete resolution of the severe dyskinesias.

KW - Deep brain stimulation

KW - Dyskinesias

KW - Movement disorder

KW - Neuromodulation

KW - Parkinson

KW - Tractography

KW - White matter

UR - https://www.scopus.com/pages/publications/85118100510

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Deep Brain Stimulation of the Pallidofugal Pathways to Rescue Severe Life-Threatening Dyskinesias after STN-DBS Lead Implantation

Abstract

Keywords

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