TY - GEN
T1 - Decoding dendritic cell function through module and network analysis
AU - Pandey, Gaurav
AU - Cohain, Ariella
AU - Miller, Jennifer
AU - Merad, Miriam
PY - 2012
Y1 - 2012
N2 - Dendritic cells (DCs) serve as the sentinels of the immune system by informing the system about external stimuli, based on which an adaptive response can be mounted. However, not much is known about the genes and their interactions that regulate DC function. Using a large gene expression compendium, we uncover promising regulatory networks underlying the functioning of DCs and their subsets.
AB - Dendritic cells (DCs) serve as the sentinels of the immune system by informing the system about external stimuli, based on which an adaptive response can be mounted. However, not much is known about the genes and their interactions that regulate DC function. Using a large gene expression compendium, we uncover promising regulatory networks underlying the functioning of DCs and their subsets.
KW - Clustering
KW - Dendritic cells
KW - Gene expression data
KW - Network analysis
KW - Transcription factors
UR - http://www.scopus.com/inward/record.url?scp=84869430631&partnerID=8YFLogxK
U2 - 10.1145/2382936.2383047
DO - 10.1145/2382936.2383047
M3 - Conference contribution
AN - SCOPUS:84869430631
SN - 9781450316705
T3 - 2012 ACM Conference on Bioinformatics, Computational Biology and Biomedicine, BCB 2012
SP - 627
EP - 628
BT - 2012 ACM Conference on Bioinformatics, Computational Biology and Biomedicine, BCB 2012
T2 - 2012 ACM Conference on Bioinformatics, Computational Biology and Biomedicine, BCB 2012
Y2 - 7 October 2012 through 10 October 2012
ER -