Deactivation of LVAD support for myocardial recovery—surgical perspectives

Ian Nickel, Evgenij Potapov, Benjamin Sun, Daniel Zimpfer, Antigone Koliopoulou, Iki Adachi, Anelechi Anyanwu, Volkmar Falk, Pavan Atluri, Gloria Faerber, Daniel Goldstein, Leora Yarboro, Mark S. Slaughter, Carmelo Milano, Masaki Tsukashita, David D'Alessandro, Scott Silvestry, Hristo Kirov, Swaroop Bommareddi, Pia LanmüllerTorsten Doenst, Craig H. Selzman

Research output: Contribution to journalReview articlepeer-review

Abstract

Left ventricular assist devices (LVADs) are excellent therapies for advanced heart failure patients either bridged to transplant or for lifetime use. LVADs also allow for reverse remodeling of the failing heart that is often associated with functional improvement. Indeed, growing enthusiasm exists to better understand this population of patients, whereby the LVAD is used as an adjunct to mediate myocardial recovery. When patients achieve benchmarks suggesting that they no longer need LVAD support, questions related to the discontinuation of LVAD therapy become front and center. The purpose of this review is to provide a surgical perspective on the practical and technical issues surrounding LVAD deactivation.

Original languageEnglish
JournalJournal of Heart and Lung Transplantation
DOIs
StateAccepted/In press - 2024

Keywords

  • decommissioning
  • explant
  • heart failure
  • mechanical circulatory support
  • myocardial recovery
  • VAD

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