De novo deletions and duplications of 17q25.3 cause susceptibility to cardiovascular malformations

Keyphrases

• Duplication 100%
• Cardiovascular Malformations 100%
• Cardiac Phenotype 75%
• Bioinformatics Analysis 50%
• Human Tissue 25%
• Multiple Genes 25%
• Unrelated Individuals 25%
• Protein-protein Interaction Network 25%
• Ventricular Septal Defect 25%
• Cincinnati 25%
• Array Comparative Genomic Hybridization (aCGH) 25%
• Genomic Disorders 25%
• Medical Genetics 25%
• Haploinsufficiency 25%
• Training Set 25%
• Atrial Septal Defect 25%
• High Penetrance 25%
• Children's Hospital 25%
• Cardiac Disease 25%
• Cardiac Malformation 25%
• Patent Ductus Arteriosus 25%
• Cardiac Lesions 25%
• Aortic Coarctation 25%
• Genetic Laboratory 25%
• Non-recurrent 25%
• Annotation System 25%
• Cardiovascular Defects 25%
• Anomalous Pulmonary Venous Return 25%
• Tissue Expression Pattern 25%
• Submicroscopic Deletion 25%
• Subtelomeric Region 25%
• Segmental Aneusomy 25%
• Plausible Drivers 25%
• College of Medicine 25%
• Genomic Segment 25%
• Pathogenicity Score 25%

Biochemistry, Genetics and Molecular Biology

• Bioinformatics Analysis 100%
• Cytogenetics 50%
• Penetrance 50%
• Array Comparative Genomic Hybridization 50%
• Medical Genetics 50%
• Haploinsufficiency 50%
• Genetic Background 50%
• Venous Return 50%
• Genomics 50%
• Protein-Protein Interaction Networks 50%