TY - JOUR
T1 - Data on atherosclerosis specific antibody conjugation to nanoemulsions
AU - Prévot, Geoffrey
AU - Duonor-Cérutti, Martine
AU - Larivière, Mélusine
AU - Laroche-Traineau, Jeanny
AU - Jacobin-Valat, Marie Josée
AU - Barthélémy, Philippe
AU - Clofent-Sanchez, Gisèle
AU - Crauste-Manciet, Sylvie
N1 - Publisher Copyright:
© 2017
PY - 2017/12
Y1 - 2017/12
N2 - This article present data related to the publication entitled “Iron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imaging” (Prévot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scFv-Fc TEG4-2C antibody, specific of platelets within the atheroma plaque. For molecular targeting purpose, atheroma specific antibody was conjugated to nanoemulsions (NEs) using a heterobifunctional linker (DSPE-PEG-maleimide). Atheroma labelling was assayed by immunochemistry on arterial sections from rabbits.
AB - This article present data related to the publication entitled “Iron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imaging” (Prévot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scFv-Fc TEG4-2C antibody, specific of platelets within the atheroma plaque. For molecular targeting purpose, atheroma specific antibody was conjugated to nanoemulsions (NEs) using a heterobifunctional linker (DSPE-PEG-maleimide). Atheroma labelling was assayed by immunochemistry on arterial sections from rabbits.
UR - https://www.scopus.com/pages/publications/85032724797
U2 - 10.1016/j.dib.2017.10.058
DO - 10.1016/j.dib.2017.10.058
M3 - Article
AN - SCOPUS:85032724797
SN - 2352-3409
VL - 15
SP - 824
EP - 827
JO - Data in Brief
JF - Data in Brief
ER -