Transposable elements (TEs), which make up almost half of the human genome, often display altered expression in cancers. Here, we review recent progress in elucidating the role of TEs as mediators of immune responses in cancer and discuss how novel therapeutic strategies can harness TE immunogenicity for cancer immunotherapy.

Original languageEnglish
Pages (from-to)792-797
Number of pages6
JournalCancer Cell
Issue number8
StatePublished - 8 Aug 2022


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