D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice

  • Esra A. Akbay
  • , Javid Moslehi
  • , Camilla L. Christensen
  • , Supriya Saha
  • , Jeremy H. Tchaicha
  • , Shakti H. Ramkissoon
  • , Kelly M. Stewart
  • , Julian Carretero
  • , Eiki Kikuchi
  • , Haikuo Zhang
  • , Travis J. Cohoon
  • , Stuart Murray
  • , Wei Liu
  • , Kazumasa Uno
  • , Sudeshna Fisch
  • , Kristen Jones
  • , Sushma Gurumurthy
  • , Camelia Gliser
  • , Sung Choe
  • , Marie Keenan
    • Jaekyoung Son, Illana Stanley, Julie A. Losman, Robert Padera, Roderick T. Bronson, John M. Asara, Omar Abdel-Wahab, Philip C. Amrein, Amir T. Fathi, Nika N. Danial, Alec C. Kimmelman, Andrew L. Kung, Keith L. Ligon, Katharine E. Yen, William G. Kaelin, Nabeel Bardeesy, Kwok Kin Wong

Research output: Contribution to journal › Article › peer-review

77 Scopus citations

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Keyphrases

Pharmacology, Toxicology and Pharmaceutical Science

Neuroscience

Biochemistry, Genetics and Molecular Biology