Cycloplegic Provocative Testing After Topical Administration of Steroids

Laurence S. Harris, Miles A. Galin, Thomas W. Mittag

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11 Scopus citations


Elevation of intraocular pressure after the topical application of cyloplegic, though rarely noted in the normal population, is seen in some 25% of the open angle glaucomatous population. No positive cycloplegic provocative responses were elicited from a population of 58 normals. After three weeks of treatment with topically administered dexamethasone, however, a 19% incidence of positive cycloplegic provocative tests was found in this same group. No correlation was noted between poststeroid intraocular pressure and cyloplegic-induced pressure elevation, but a statistically significant, inverse correlation between positive cycloplegic responses and outflow facility was noted after steroid treatment. The phenomenon of cycloplegic-induced pressure elevation thus appears to be related more closely to impaired outflow facility than to pretesting intraocular pressure levels.

Original languageEnglish
Pages (from-to)12-14
Number of pages3
JournalArchives of Ophthalmology
Issue number1
StatePublished - Jul 1971
Externally publishedYes


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