CXCR3-CXCL9: It's All in the Tumor

Etienne Humblin; Alice O. Kamphorst

doi:10.1016/j.immuni.2019.05.013

CXCR3-CXCL9: It's All in the Tumor

Etienne Humblin
, Alice O. Kamphorst

Research output: Contribution to journal › Short survey › peer-review

59 Scopus citations

Abstract

In this issue of Immunity, Chow et al. (2019) show that the CXCR3-CXCL9 axis is required for reinvigoration of intratumoral CD8⁺ T cell responses in response to PD-1 blockade and demonstrate that local guidance to dendritic cells, rather than recruitment of T cells into the tumor, underlies the importance of this chemokine axis.

Original language	English
Pages (from-to)	1347-1349
Number of pages	3
Journal	Immunity
Volume	50
Issue number	6
DOIs	https://doi.org/10.1016/j.immuni.2019.05.013
State	Published - 18 Jun 2019

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@article{c96a0d3a991d4911a050816d4687aa7e,

title = "CXCR3-CXCL9: It's All in the Tumor",

abstract = "In this issue of Immunity, Chow et al. (2019) show that the CXCR3-CXCL9 axis is required for reinvigoration of intratumoral CD8+ T cell responses in response to PD-1 blockade and demonstrate that local guidance to dendritic cells, rather than recruitment of T cells into the tumor, underlies the importance of this chemokine axis.",

author = "Etienne Humblin and Kamphorst, \{Alice O.\}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = jun,

day = "18",

doi = "10.1016/j.immuni.2019.05.013",

language = "English",

volume = "50",

pages = "1347--1349",

journal = "Immunity",

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TY - JOUR

T1 - CXCR3-CXCL9

T2 - It's All in the Tumor

AU - Humblin, Etienne

AU - Kamphorst, Alice O.

PY - 2019/6/18

Y1 - 2019/6/18

N2 - In this issue of Immunity, Chow et al. (2019) show that the CXCR3-CXCL9 axis is required for reinvigoration of intratumoral CD8+ T cell responses in response to PD-1 blockade and demonstrate that local guidance to dendritic cells, rather than recruitment of T cells into the tumor, underlies the importance of this chemokine axis.

AB - In this issue of Immunity, Chow et al. (2019) show that the CXCR3-CXCL9 axis is required for reinvigoration of intratumoral CD8+ T cell responses in response to PD-1 blockade and demonstrate that local guidance to dendritic cells, rather than recruitment of T cells into the tumor, underlies the importance of this chemokine axis.

UR - https://www.scopus.com/pages/publications/85066330833

U2 - 10.1016/j.immuni.2019.05.013

DO - 10.1016/j.immuni.2019.05.013

M3 - Short survey

C2 - 31216458

AN - SCOPUS:85066330833

SN - 1074-7613

VL - 50

SP - 1347

EP - 1349

JO - Immunity

JF - Immunity

IS - 6

ER -

CXCR3-CXCL9: It's All in the Tumor

Abstract

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