CXCR3-CXCL9: It's All in the Tumor

Etienne Humblin, Alice O. Kamphorst

Research output: Contribution to journalShort surveypeer-review

27 Scopus citations

Abstract

In this issue of Immunity, Chow et al. (2019) show that the CXCR3-CXCL9 axis is required for reinvigoration of intratumoral CD8+ T cell responses in response to PD-1 blockade and demonstrate that local guidance to dendritic cells, rather than recruitment of T cells into the tumor, underlies the importance of this chemokine axis.

Original languageEnglish
Pages (from-to)1347-1349
Number of pages3
JournalImmunity
Volume50
Issue number6
DOIs
StatePublished - 18 Jun 2019

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