Cutaneous Polyarteritis nodosa after streptococcal necrotizing fasciitis

Ronnit Hamuy Stein, Robert G. Phelps, Allen N. Sapadin

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9 Scopus citations


Polyarteritis nodosa (PAN) is a necrotizing arteritis of small and medium-sized vessels. It may present with hypertension and/or renal insufficiency. Peripheral neuropathy, myopathy, joint pains, testicular pain, and ischemic myalgias may also be seen. Gastrointestinal involvement may lead to gangrene of the bowel, peritonitis, perforation, intra-abdominal hemorrhage, and pancreatitis. The cutaneous manifestations include tender subcutaneous nodules grouped along the course of superficial arteries of the lower extremities, with or without an overlying livedo reticularis. Although multisystem involvement is characteristic, sometimes only one organ or system may be involved. Associations with viral hepatitis (both B and C) and streptococcal infection have been established for PAN. Recurrent strep infections of the upper respiratory tract, streptococcal glomerulonephritis and rheumatic fever have previously been linked to PAN. This report extends the spectrum of associated streptococcal infections to include necrotizing fasciitis.

Original languageEnglish
Pages (from-to)336-338
Number of pages3
JournalMount Sinai Journal of Medicine
Issue number4-5
StatePublished - Sep 2001


  • Necrotizing fasciitis
  • Polyarteritis nodosa


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