Current laser therapy options for endoscopic treatment of upper tract urothelial carcinoma

Benjamin W. Zollinger; Ezra J. Shoen; Charles F. Gresham; Michael J. Whalen

doi:10.1097/CU9.0000000000000158

Current laser therapy options for endoscopic treatment of upper tract urothelial carcinoma

Benjamin W. Zollinger, Ezra J. Shoen, Charles F. Gresham, Michael J. Whalen

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Endoscopic management via retrograde ureteroscopic laser ablation of upper tract urothelial carcinoma (UTUC) has become the preferred treatment modality for low-risk tumors. The most popular ablative lasers over the past 15-20 years have been the holmium:yttrium-aluminum-garnet (Ho:YAG) and neodymium (Nd:YAG) lasers, but recently the thulium (Th:YAG) laser has emerged as a potential alternative. This review compares the mechanism of action, physiological properties and effects, and oncologic outcomes of Ho:YAG/Nd:YAG lasers versus the Th:YAG laser for UTUC treatment. Potential advantages of the Th:YAG laser over existing technologies are outlined, followed by a discussion of emerging laser technologies in UTUC management.

Original language	English
Pages (from-to)	62-67
Number of pages	6
Journal	Current Urology
Volume	17
Issue number	1
DOIs	https://doi.org/10.1097/CU9.0000000000000158
State	Published - 1 Mar 2023

Keywords

Endoscopic management
Holmium laser
Laser ablation
Thulium laser
Upper tract urothelial carcinoma

Access to Document

10.1097/CU9.0000000000000158

Cite this

@article{cd0db0b51c124f9998eb23dc62362e55,

title = "Current laser therapy options for endoscopic treatment of upper tract urothelial carcinoma",

abstract = "Endoscopic management via retrograde ureteroscopic laser ablation of upper tract urothelial carcinoma (UTUC) has become the preferred treatment modality for low-risk tumors. The most popular ablative lasers over the past 15-20 years have been the holmium:yttrium-aluminum-garnet (Ho:YAG) and neodymium (Nd:YAG) lasers, but recently the thulium (Th:YAG) laser has emerged as a potential alternative. This review compares the mechanism of action, physiological properties and effects, and oncologic outcomes of Ho:YAG/Nd:YAG lasers versus the Th:YAG laser for UTUC treatment. Potential advantages of the Th:YAG laser over existing technologies are outlined, followed by a discussion of emerging laser technologies in UTUC management.",

keywords = "Endoscopic management, Holmium laser, Laser ablation, Thulium laser, Upper tract urothelial carcinoma",

author = "Zollinger, {Benjamin W.} and Shoen, {Ezra J.} and Gresham, {Charles F.} and Whalen, {Michael J.}",

year = "2023",

month = mar,

day = "1",

doi = "10.1097/CU9.0000000000000158",

language = "English",

volume = "17",

pages = "62--67",

journal = "Current Urology",

issn = "1661-7649",

publisher = "Lippincott Williams and Wilkins",

number = "1",

}

TY - JOUR

T1 - Current laser therapy options for endoscopic treatment of upper tract urothelial carcinoma

AU - Zollinger, Benjamin W.

AU - Shoen, Ezra J.

AU - Gresham, Charles F.

AU - Whalen, Michael J.

PY - 2023/3/1

Y1 - 2023/3/1

N2 - Endoscopic management via retrograde ureteroscopic laser ablation of upper tract urothelial carcinoma (UTUC) has become the preferred treatment modality for low-risk tumors. The most popular ablative lasers over the past 15-20 years have been the holmium:yttrium-aluminum-garnet (Ho:YAG) and neodymium (Nd:YAG) lasers, but recently the thulium (Th:YAG) laser has emerged as a potential alternative. This review compares the mechanism of action, physiological properties and effects, and oncologic outcomes of Ho:YAG/Nd:YAG lasers versus the Th:YAG laser for UTUC treatment. Potential advantages of the Th:YAG laser over existing technologies are outlined, followed by a discussion of emerging laser technologies in UTUC management.

AB - Endoscopic management via retrograde ureteroscopic laser ablation of upper tract urothelial carcinoma (UTUC) has become the preferred treatment modality for low-risk tumors. The most popular ablative lasers over the past 15-20 years have been the holmium:yttrium-aluminum-garnet (Ho:YAG) and neodymium (Nd:YAG) lasers, but recently the thulium (Th:YAG) laser has emerged as a potential alternative. This review compares the mechanism of action, physiological properties and effects, and oncologic outcomes of Ho:YAG/Nd:YAG lasers versus the Th:YAG laser for UTUC treatment. Potential advantages of the Th:YAG laser over existing technologies are outlined, followed by a discussion of emerging laser technologies in UTUC management.

KW - Endoscopic management

KW - Holmium laser

KW - Laser ablation

KW - Thulium laser

KW - Upper tract urothelial carcinoma

UR - http://www.scopus.com/inward/record.url?scp=85151837379&partnerID=8YFLogxK

U2 - 10.1097/CU9.0000000000000158

DO - 10.1097/CU9.0000000000000158

M3 - Review article

AN - SCOPUS:85151837379

SN - 1661-7649

VL - 17

SP - 62

EP - 67

JO - Current Urology

JF - Current Urology

IS - 1

ER -

Current laser therapy options for endoscopic treatment of upper tract urothelial carcinoma

Abstract

Keywords

Access to Document

Fingerprint

Cite this