Cure of undifferentiated small cell carcinoma of the urinary bladder with M-VAC chemotherapy

Robert J. Nejat; Ravjeer Purohit; Erik T. Goluboff; Daniel Petrylak; Mark A. Rubin; Mitchell C. Benson

doi:10.1016/S1078-1439(00)00098-3

Cure of undifferentiated small cell carcinoma of the urinary bladder with M-VAC chemotherapy

Robert J. Nejat, Ravjeer Purohit, Erik T. Goluboff, Daniel Petrylak, Mark A. Rubin, Mitchell C. Benson

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Small cell carcinoma (SCC) of the urinary bladder is a rare, aggressive malignancy with approximately 135 cases reported in the literature. Treatments have included chemotherapy, radical surgery, radiotherapy, and combinations of these. We present the apparent cure of a 73-year-old man who presented with clinical stage T2 SCC of the urinary bladder. He was treated with three cycles of methotrexate, vinblastine, Adriamycin (doxorubicin), and cisplatin (M-VAC) chemotherapy. Subsequent radical cystoprostatectomy revealed no pathologic evidence of tumor. The patient is alive and well with no evidence of recurrence 3 years post cystectomy. A brief review of the literature is also presented.

Original language	English
Pages (from-to)	53-55
Number of pages	3
Journal	Urologic Oncology: Seminars and Original Investigations
Volume	6
Issue number	2
DOIs	https://doi.org/10.1016/S1078-1439(00)00098-3
State	Published - 2001
Externally published	Yes

Keywords

Bladder neoplasms
Carcinoma, small cell
Chemotherapy, adjuvant

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10.1016/S1078-1439(00)00098-3

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title = "Cure of undifferentiated small cell carcinoma of the urinary bladder with M-VAC chemotherapy",

abstract = "Small cell carcinoma (SCC) of the urinary bladder is a rare, aggressive malignancy with approximately 135 cases reported in the literature. Treatments have included chemotherapy, radical surgery, radiotherapy, and combinations of these. We present the apparent cure of a 73-year-old man who presented with clinical stage T2 SCC of the urinary bladder. He was treated with three cycles of methotrexate, vinblastine, Adriamycin (doxorubicin), and cisplatin (M-VAC) chemotherapy. Subsequent radical cystoprostatectomy revealed no pathologic evidence of tumor. The patient is alive and well with no evidence of recurrence 3 years post cystectomy. A brief review of the literature is also presented.",

keywords = "Bladder neoplasms, Carcinoma, small cell, Chemotherapy, adjuvant",

author = "Nejat, \{Robert J.\} and Ravjeer Purohit and Goluboff, \{Erik T.\} and Daniel Petrylak and Rubin, \{Mark A.\} and Benson, \{Mitchell C.\}",

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doi = "10.1016/S1078-1439(00)00098-3",

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T1 - Cure of undifferentiated small cell carcinoma of the urinary bladder with M-VAC chemotherapy

AU - Nejat, Robert J.

AU - Purohit, Ravjeer

AU - Goluboff, Erik T.

AU - Petrylak, Daniel

AU - Rubin, Mark A.

AU - Benson, Mitchell C.

PY - 2001

Y1 - 2001

N2 - Small cell carcinoma (SCC) of the urinary bladder is a rare, aggressive malignancy with approximately 135 cases reported in the literature. Treatments have included chemotherapy, radical surgery, radiotherapy, and combinations of these. We present the apparent cure of a 73-year-old man who presented with clinical stage T2 SCC of the urinary bladder. He was treated with three cycles of methotrexate, vinblastine, Adriamycin (doxorubicin), and cisplatin (M-VAC) chemotherapy. Subsequent radical cystoprostatectomy revealed no pathologic evidence of tumor. The patient is alive and well with no evidence of recurrence 3 years post cystectomy. A brief review of the literature is also presented.

AB - Small cell carcinoma (SCC) of the urinary bladder is a rare, aggressive malignancy with approximately 135 cases reported in the literature. Treatments have included chemotherapy, radical surgery, radiotherapy, and combinations of these. We present the apparent cure of a 73-year-old man who presented with clinical stage T2 SCC of the urinary bladder. He was treated with three cycles of methotrexate, vinblastine, Adriamycin (doxorubicin), and cisplatin (M-VAC) chemotherapy. Subsequent radical cystoprostatectomy revealed no pathologic evidence of tumor. The patient is alive and well with no evidence of recurrence 3 years post cystectomy. A brief review of the literature is also presented.

KW - Bladder neoplasms

KW - Carcinoma, small cell

KW - Chemotherapy, adjuvant

UR - https://www.scopus.com/pages/publications/0035143192

U2 - 10.1016/S1078-1439(00)00098-3

DO - 10.1016/S1078-1439(00)00098-3

M3 - Article

AN - SCOPUS:0035143192

SN - 1078-1439

VL - 6

SP - 53

EP - 55

JO - Urologic Oncology: Seminars and Original Investigations

JF - Urologic Oncology: Seminars and Original Investigations

IS - 2

ER -

Cure of undifferentiated small cell carcinoma of the urinary bladder with M-VAC chemotherapy

Abstract

Keywords

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