Cryoglobulins, Cryofibrinogenemia, and Pyroglobulins

Peter D. Gorevic, Dennis Galanakis

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Cryoglobulinemia is one of a group of syndromes characterized by the induction of clinical and/or laboratory abnormalities by cold. Cryoglobulins are immunoglobulins (Igs) that precipitate out of solution below core body temperatures, either as a single isotype (simple cryoglobulins) or as immune complexes in which both antibody and antigen are Igs (mixed cryoglobulins). In some instances, cryoglobulinemia may coexist with other related but usually distinct forms of cold hypersensitivity, such as Raynaud's phenomenon, cold agglutinin activity, or cold-dependent activation of complement (CDAC) (1).

Original languageEnglish
Title of host publicationManual of Molecular and Clinical Laboratory Immunology, Eighth Edition
Publisherwiley
Pages101-111
Number of pages11
ISBN (Electronic)9781683670773
ISBN (Print)9781555818715
DOIs
StatePublished - 1 Jan 2016

Fingerprint

Dive into the research topics of 'Cryoglobulins, Cryofibrinogenemia, and Pyroglobulins'. Together they form a unique fingerprint.

Cite this