Cross-Presentation of Tumor Antigens Is Ruled by Synaptic Transfer of Vesicles among Dendritic Cell Subsets

Sreekumar Balan; Nina Bhardwaj

doi:10.1016/j.ccell.2020.05.013

Cross-Presentation of Tumor Antigens Is Ruled by Synaptic Transfer of Vesicles among Dendritic Cell Subsets

Sreekumar Balan, Nina Bhardwaj

Research output: Contribution to journal › Comment/debate

16 Scopus citations

Abstract

Migratory dendritic cells (DCs) in tumors transport antigens and share them with lymph node resident DCs through cross-presentation. In this issue of Cancer Cell, Ruhland et al. demonstrate that transport and transfer of tumor antigens in vesicles is a dominant pathway to load resident DCs for presentation to T cells.

Original language	English
Pages (from-to)	751-753
Number of pages	3
Journal	Cancer Cell
Volume	37
Issue number	6
DOIs	https://doi.org/10.1016/j.ccell.2020.05.013
State	Published - 8 Jun 2020

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@article{101e1244fae849faa189f8d0ffd66bb5,

title = "Cross-Presentation of Tumor Antigens Is Ruled by Synaptic Transfer of Vesicles among Dendritic Cell Subsets",

abstract = "Migratory dendritic cells (DCs) in tumors transport antigens and share them with lymph node resident DCs through cross-presentation. In this issue of Cancer Cell, Ruhland et al. demonstrate that transport and transfer of tumor antigens in vesicles is a dominant pathway to load resident DCs for presentation to T cells.",

author = "Sreekumar Balan and Nina Bhardwaj",

note = "Publisher Copyright: {\textcopyright} 2020",

year = "2020",

month = jun,

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doi = "10.1016/j.ccell.2020.05.013",

language = "English",

volume = "37",

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journal = "Cancer Cell",

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T1 - Cross-Presentation of Tumor Antigens Is Ruled by Synaptic Transfer of Vesicles among Dendritic Cell Subsets

AU - Balan, Sreekumar

AU - Bhardwaj, Nina

PY - 2020/6/8

Y1 - 2020/6/8

N2 - Migratory dendritic cells (DCs) in tumors transport antigens and share them with lymph node resident DCs through cross-presentation. In this issue of Cancer Cell, Ruhland et al. demonstrate that transport and transfer of tumor antigens in vesicles is a dominant pathway to load resident DCs for presentation to T cells.

AB - Migratory dendritic cells (DCs) in tumors transport antigens and share them with lymph node resident DCs through cross-presentation. In this issue of Cancer Cell, Ruhland et al. demonstrate that transport and transfer of tumor antigens in vesicles is a dominant pathway to load resident DCs for presentation to T cells.

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U2 - 10.1016/j.ccell.2020.05.013

DO - 10.1016/j.ccell.2020.05.013

M3 - Comment/debate

C2 - 32516584

AN - SCOPUS:85085686698

SN - 1535-6108

VL - 37

SP - 751

EP - 753

JO - Cancer Cell

JF - Cancer Cell

IS - 6

ER -

Cross-Presentation of Tumor Antigens Is Ruled by Synaptic Transfer of Vesicles among Dendritic Cell Subsets

Abstract

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