Cross-bridge cycling gives rise to spatiotemporal heterogeneity of dynamic subcellular mechanics in cardiac myocytes probed with atomic force microscopy

Keyphrases

• Myocytes 100%
• Stiffness 100%
• Atomic Force Microscopy 100%
• Cross-bridge Cycling 100%
• Beating Cardiomyocytes 100%
• Spatiotemporal Heterogeneity 100%
• Cardiac Function 50%
• Spatiotemporal 50%
• Heterogeneous Patterns 50%
• Elastography 50%
• Disease Process 50%
• Mechanical Properties 50%
• Sarcomeric Structure 50%
• Pharmacological Treatment 50%
• Atomic Force Microscope 50%
• Neonatal Rat Cardiomyocytes 50%
• Apparent Modulus 50%
• Cardiac Structure 50%
• Micromechanics 50%
• Contractile Activity 50%
• Spatiotemporal Variation 50%
• Myofibril 50%
• Apparent Elastic Modulus 50%
• Actin-myosin 50%
• Dynamic Mechanical 50%
• Blebbistatin 50%
• Major Axis 50%
• Myosin Cross-bridges 50%
• Mechanical Mapping 50%

Engineering

• Atomic Force Microscopy 100%
• Cardiomyocytes 100%
• Cardiac Myocytes 100%
• Subcellular Biomechanics 100%
• Subcellular 66%
• Atomic Force Microscope 33%
• Major Axis 33%
• Modulus of Elasticity 33%

Biochemistry, Genetics and Molecular Biology

• Cardiac Muscle Cell 100%
• Atomic Force Microscopy 100%
• Rigidity 50%
• Actin 25%
• Young Modulus 25%
• Myofibril 25%