Abstract
Crohn’s disease (CD) is characterized by chronic intestinal inflammation. The exact etiology remains unclear; however, research continues to advance at a rapid pace to try and uncover the mysteries of this heterogeneous inflammatory process. Two important discoveries have been made in the past decade: the role of genetic susceptibility in CD and the introduction of monoclonal antibodies targeted to tumor-necrosis factor alpha (TNFa). This chapter will highlight advances in the diagnosis and management of CD and how genetics is shaping the individualization of treatment approaches.
Original language | English |
---|---|
Title of host publication | Gut Instincts |
Subtitle of host publication | A Clinician’s Handbook of Digestive and Liver Diseases |
Publisher | CRC Press |
Pages | 117-122 |
Number of pages | 6 |
ISBN (Electronic) | 9781040143445 |
ISBN (Print) | 9781556429774 |
DOIs | |
State | Published - 1 Jan 2024 |
Externally published | Yes |