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Creation and correction of vertebral wedge deformity by mechanical modulation of growth

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The objectives of this study were to test the hypotheses that a vertebral wedge deformity created by asymmetrical loading will correct after reversal of the load asymmetry and that vertebral growth will return to normal following load removal. An external fixator was applied to the tails of two groups of 12 rats each. The fixator applied an axial compression of 60% body weight together with an imposed angulation of 30° and thus asymmetrically loaded the intervening vertebra and discs. After an initial asymmetric loading for four weeks the loading was reversed for four weeks in group I animals and removed in group II animals. Vertebral wedging was measured using radiographs and fluorochrome labeling. This study showed Uiat a wedge deformity can be corrected by reversing the load used to create it and that vertebral growth rates will return to normal after removal of the external loads, demonstrating that growdi is not permanenUy affected by applied loading.

Original languageEnglish
Title of host publicationResearch into Spinal Deformities 2
PublisherIOS Press
Pages234-237
Number of pages4
ISBN (Print)9051994303, 9789051994308
DOIs
StatePublished - 1999
Externally publishedYes
Event2nd Biannual Meeting of the International Research Society of Spinal Deformities, IRSSD 1998 - Burlington, VT, United States
Duration: 1 Jun 19981 Jun 1998

Publication series

NameStudies in Health Technology and Informatics
Volume59
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Conference

Conference2nd Biannual Meeting of the International Research Society of Spinal Deformities, IRSSD 1998
Country/TerritoryUnited States
CityBurlington, VT
Period1/06/981/06/98

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