Craniopharyngioma arising de novo in middle age. Case report

Marc S. Arginteanu, Karin Hague, Robert Zimmerman, Mark J. Kupersmith, John H. Shaiu, John Schaeffer, Kalmon D. Post

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The authors report the case of a 55-year old woman who developed a symptomatic craniopharyngioma within 2 years of obtaining a normal magnetic resonance image of her brain. Craniopharyngiomas are histologically benign tumors. They are thought to arise from embryonic remnants of Rathke's pouch and sac and to manifest themselves clinically after a steady growth that commences in fetal life. To the authors' knowledge, this is the first report that documents a tumor arising de novo in the sixth decade of life. This report appears to challenge the concept of the origin and natural history of craniopharyngiomas.

Original languageEnglish
Pages (from-to)1046-1048
Number of pages3
JournalJournal of Neurosurgery
Issue number6
StatePublished - Jun 1997


  • craniopharyngioma
  • developmental anomaly
  • magnetic resonance imaging


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