Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: Stereoselective synthesis of Z-configured allylic amines

Renhong Sun; Jun Liu; Shuang Yang; Ming Chen; Ning Sun; Haoyi Chen; Xin Xie; Xu You; Shi Li; Yuanhong Liu

doi:10.1039/c5cc00950b

Cp₂TiCl₂-catalyzed cis-hydroalumination of propargylic amines with Red-Al: Stereoselective synthesis of Z-configured allylic amines

Renhong Sun
, Jun Liu
, Shuang Yang
, Ming Chen
, Ning Sun
, Haoyi Chen
, Xin Xie
, Xu You
, Shi Li
, Yuanhong Liu

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

A titanium-catalyzed cis-hydroalumination of propargylic amines with Red-Al is described, which provides an efficient way to produce Z-configured allylic amines in good to excellent yields with high stereoselectivity and good regioselectivity. The hydride-bridged Al/Ti bimetallic species may act as a real catalyst in this reaction.

Original language	English
Pages (from-to)	6426-6429
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	29
DOIs	https://doi.org/10.1039/c5cc00950b
State	Published - 14 Apr 2015
Externally published	Yes

Access to Document

10.1039/c5cc00950b

Cite this

@article{35d28fb16a214ba19b2297c5afc90800,

title = "Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: Stereoselective synthesis of Z-configured allylic amines",

abstract = "A titanium-catalyzed cis-hydroalumination of propargylic amines with Red-Al is described, which provides an efficient way to produce Z-configured allylic amines in good to excellent yields with high stereoselectivity and good regioselectivity. The hydride-bridged Al/Ti bimetallic species may act as a real catalyst in this reaction.",

author = "Renhong Sun and Jun Liu and Shuang Yang and Ming Chen and Ning Sun and Haoyi Chen and Xin Xie and Xu You and Shi Li and Yuanhong Liu",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2015.",

year = "2015",

month = apr,

day = "14",

doi = "10.1039/c5cc00950b",

language = "English",

volume = "51",

pages = "6426--6429",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "29",

}

TY - JOUR

T1 - Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al

T2 - Stereoselective synthesis of Z-configured allylic amines

AU - Sun, Renhong

AU - Liu, Jun

AU - Yang, Shuang

AU - Chen, Ming

AU - Sun, Ning

AU - Chen, Haoyi

AU - Xie, Xin

AU - You, Xu

AU - Li, Shi

AU - Liu, Yuanhong

PY - 2015/4/14

Y1 - 2015/4/14

N2 - A titanium-catalyzed cis-hydroalumination of propargylic amines with Red-Al is described, which provides an efficient way to produce Z-configured allylic amines in good to excellent yields with high stereoselectivity and good regioselectivity. The hydride-bridged Al/Ti bimetallic species may act as a real catalyst in this reaction.

AB - A titanium-catalyzed cis-hydroalumination of propargylic amines with Red-Al is described, which provides an efficient way to produce Z-configured allylic amines in good to excellent yields with high stereoselectivity and good regioselectivity. The hydride-bridged Al/Ti bimetallic species may act as a real catalyst in this reaction.

UR - https://www.scopus.com/pages/publications/84925858141

U2 - 10.1039/c5cc00950b

DO - 10.1039/c5cc00950b

M3 - Article

C2 - 25765939

AN - SCOPUS:84925858141

SN - 1359-7345

VL - 51

SP - 6426

EP - 6429

JO - Chemical Communications

JF - Chemical Communications

IS - 29

ER -

Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: Stereoselective synthesis of Z-configured allylic amines

Abstract

Access to Document

Fingerprint

Cite this

Cp₂TiCl₂-catalyzed cis-hydroalumination of propargylic amines with Red-Al: Stereoselective synthesis of Z-configured allylic amines