A web resource for SARS-CoV-2-related structural models

Dariusz Brzezinski, Marcin Kowiel, David R. Cooper, Marcin Cymborowski, Marek Grabowski, Alexander Wlodawer, Zbigniew Dauter, Ivan G. Shabalin, Miroslaw Gilski, Bernhard Rupp, Mariusz Jaskolski, Wladek Minor

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


The COVID-19 pandemic has triggered numerous scientific activities aimed at understanding the SARS-CoV-2 virus and ultimately developing treatments. Structural biologists have already determined hundreds of experimental X-ray, cryo-EM, and NMR structures of proteins and nucleic acids related to this coronavirus, and this number is still growing. To help biomedical researchers, who may not necessarily be experts in structural biology, navigate through the flood of structural models, we have created an online resource,, that aggregates expert-verified information about SARS-CoV-2-related macromolecular models. In this article, we describe this web resource along with the suite of tools and methodologies used for assessing the structures presented therein.

Original languageEnglish
Pages (from-to)115-124
Number of pages10
JournalProtein Science
Issue number1
StatePublished - Jan 2021
Externally publishedYes


  • COVID-19
  • PDB
  • SARS-CoV-2
  • coronavirus
  • ligand assessment
  • reproducibility
  • structure validation
  • structure-guided drug discovery


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