Cost-effectiveness of diagnostic evaluation strategies for individuals with stable chest pain syndrome and suspected coronary artery disease

James K. Min, Amanda Gilmore, Erica C. Jones, Daniel S. Berman, Wijnand J. Stuijfzand, Leslee J. Shaw, Ken O'Day, Ibrahim Danad

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Purpose To determine lifetime cost-effectiveness of diagnostic evaluation strategies for individuals with stable chest pain and suspected coronary artery disease (CAD). Methods Exercise treadmill testing (ETT), stress echocardiography (SE), myocardial perfusion scintigraphy (MPS), coronary computed tomographic angiography (CCTA), and invasive coronary angiography (ICA) were assessed alone, or in succession to each other. Results Initial ETT followed by imaging wherein ETT was equivocal or unable to be performed appeared more cost-effective than any strategy employing initial testing by imaging. Conclusion As pre-test likelihood of CAD varies, different modalities including SE, CCTA, and MPS result in improved costs and enhanced effectiveness.

Original languageEnglish
Pages (from-to)97-105
Number of pages9
JournalClinical Imaging
Volume43
DOIs
StatePublished - 1 May 2017
Externally publishedYes

Keywords

  • Computed tomography
  • Cost effectiveness
  • Echocardiography
  • Invasive angiography
  • Myocardial perfusion SPECT
  • Stress testing

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