Corticosteroid-induced uveitis

Jose Costa Martins; Jacob T. Wilensky; Carl F. Asseff; Stephen A. Obstbaum; Kenneth M. Buerk

doi:10.1016/0002-9394(74)90448-6

Corticosteroid-induced uveitis

Jose Costa Martins, Jacob T. Wilensky, Carl F. Asseff, Stephen A. Obstbaum, Kenneth M. Buerk

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Sixteen cases of acute anterior uveitis occurred in association with topical corticosteroid administration. Fifteen of these were with dexamethasone sodium phosphate and the 16th with triamcinolone acetonide 0.5% solution. The incidence of uveitis was significantly higher in blacks (5.4%) than in whites (0.5%). There was no difference in incidence between sexes. The mean age of the uveitis patients was about a decade higher than the mean age of the unaffected subjects. No relationship was noted between uveitis and intraocular pressure response to topical corticosteroids. Retesting one of the subjects with prednisolone acetate 1% ophthalmic suspension led to the reappearance of the reaction. Retesting another patient with the vehicles used in two of the above preparations produced no ocular inflammation.

Original language	English
Pages (from-to)	433-437
Number of pages	5
Journal	American Journal of Ophthalmology
Volume	77
Issue number	4
DOIs	https://doi.org/10.1016/0002-9394(74)90448-6
State	Published - Apr 1974
Externally published	Yes

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@article{35ce499fdeb447778c798e3f286c9abb,

title = "Corticosteroid-induced uveitis",

abstract = "Sixteen cases of acute anterior uveitis occurred in association with topical corticosteroid administration. Fifteen of these were with dexamethasone sodium phosphate and the 16th with triamcinolone acetonide 0.5% solution. The incidence of uveitis was significantly higher in blacks (5.4%) than in whites (0.5%). There was no difference in incidence between sexes. The mean age of the uveitis patients was about a decade higher than the mean age of the unaffected subjects. No relationship was noted between uveitis and intraocular pressure response to topical corticosteroids. Retesting one of the subjects with prednisolone acetate 1% ophthalmic suspension led to the reappearance of the reaction. Retesting another patient with the vehicles used in two of the above preparations produced no ocular inflammation.",

author = "Martins, {Jose Costa} and Wilensky, {Jacob T.} and Asseff, {Carl F.} and Obstbaum, {Stephen A.} and Buerk, {Kenneth M.}",

note = "Funding Information: From the Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri. This study was supported in part by research grant EY 00336 from the National Eye Institute and by the following fellowships: Instituto de Alta Cultura, Lisbon, Portugal (Dr. Costa Martins), EY 53710-01 (Dr. Wilensky), EY 51613-01 (Dr. Asseff), EY 54132-01 (Dr. Obstbaum), and EY 52947-01 (Dr. Buerk).",

year = "1974",

month = apr,

doi = "10.1016/0002-9394(74)90448-6",

language = "English",

volume = "77",

pages = "433--437",

journal = "American Journal of Ophthalmology",

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TY - JOUR

T1 - Corticosteroid-induced uveitis

AU - Martins, Jose Costa

AU - Wilensky, Jacob T.

AU - Asseff, Carl F.

AU - Obstbaum, Stephen A.

AU - Buerk, Kenneth M.

N1 - Funding Information: From the Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri. This study was supported in part by research grant EY 00336 from the National Eye Institute and by the following fellowships: Instituto de Alta Cultura, Lisbon, Portugal (Dr. Costa Martins), EY 53710-01 (Dr. Wilensky), EY 51613-01 (Dr. Asseff), EY 54132-01 (Dr. Obstbaum), and EY 52947-01 (Dr. Buerk).

PY - 1974/4

Y1 - 1974/4

N2 - Sixteen cases of acute anterior uveitis occurred in association with topical corticosteroid administration. Fifteen of these were with dexamethasone sodium phosphate and the 16th with triamcinolone acetonide 0.5% solution. The incidence of uveitis was significantly higher in blacks (5.4%) than in whites (0.5%). There was no difference in incidence between sexes. The mean age of the uveitis patients was about a decade higher than the mean age of the unaffected subjects. No relationship was noted between uveitis and intraocular pressure response to topical corticosteroids. Retesting one of the subjects with prednisolone acetate 1% ophthalmic suspension led to the reappearance of the reaction. Retesting another patient with the vehicles used in two of the above preparations produced no ocular inflammation.

AB - Sixteen cases of acute anterior uveitis occurred in association with topical corticosteroid administration. Fifteen of these were with dexamethasone sodium phosphate and the 16th with triamcinolone acetonide 0.5% solution. The incidence of uveitis was significantly higher in blacks (5.4%) than in whites (0.5%). There was no difference in incidence between sexes. The mean age of the uveitis patients was about a decade higher than the mean age of the unaffected subjects. No relationship was noted between uveitis and intraocular pressure response to topical corticosteroids. Retesting one of the subjects with prednisolone acetate 1% ophthalmic suspension led to the reappearance of the reaction. Retesting another patient with the vehicles used in two of the above preparations produced no ocular inflammation.

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DO - 10.1016/0002-9394(74)90448-6

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VL - 77

SP - 433

EP - 437

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 4

ER -

Corticosteroid-induced uveitis

Abstract

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