Corrigendum to “Bidirectional juxtacrine ephrinB2/Ephs signaling promotes angiogenesis of ECs and maintains self-renewal of MSCs” [Biomaterials 172 (2018) 1–13, (S0142961218303065), (10.1016/j.biomaterials.2018.04.042)]

  • Cen Cao
  • , Ying Huang
  • , Qingming Tang
  • , Chenguang Zhang
  • , Lei Shi
  • , Jiajia Zhao
  • , Li Hu
  • , Zhewen Hu
  • , Yun Liu
  • , Lili Chen

Research output: Contribution to journalComment/debate

Abstract

The authors regret one inadvertent error presented in Fig. 1E. The representative tube formation image of hUVECs + hBMSCs(Scramble) group at 4 hours after cells were seeded on Matrigel was repeatedly inserted as the image of hUVECs + hBMSCs + IgG group at 4 hours after cells were seeded on Matrigel by a mistake during the preparation of the figures. The correct version of Fig. 1 is provided below. Furthermore, the correction does not alter any findings and conclusions reported in this article. The authors would like to apologize for any inconvenience caused.[Formula presented] Fig. 1. Disruption of forward ephrinB2/Ephs signaling from hBMSCs decreased tube formation of hUVECs. (A) Representative images of tube formation at 4 and 8 hours after cells were seeded on Matrigel. hUVECs + hBMSCs group: hUVECs co-cultured with the same amount of hBMSCs; CM (hBMSCs) group: conditioned medium of hBMSCs; hUVECs*2 group: independent culture of hUVECs twice as many. hUVECs group: independent culture of hUVECs. Scale bar: 100 μm. (B) The total tube length, number of tubules, and number of junctions in each group in Figure A at 8 hours were quantified using Image Pro Plus software. (C) Western blot of ephrinB2 expression after transfection with scramble, EFNB2-shRNA#1, and EFNB2-shRNA#2. GAPDH was used as the internal control. (D) Representative images of tube formation at 4 and 8 hours after cells were seeded on Matrigel. hUVECs were co-cultured with hBMSCs, and hBMSCs were transfected with the negative control (scramble) and lentivirus for knockdown of EFNB2 (EFNB2-shRNA#1, EFNB2-shRNA#2). Scale bar: 100 μm. (E) Representative images of tube formation of co-cultured cells containing IgG or monomeric EphB4 (mEphB4) (200 ng/mL) at 4 and 8 hours after cells were seeded on Matrigel. Scale bar: 100 μm. (F) Total tube length, number of tubules, and number of junctions in each group in Figure D at 8 hours were quantified using Image Pro Plus software. (G) Total tube length, number of tubules, and number of junctions in each group in Figure E at 8 hours were quantified using Image Pro Plus software. Data are presented as means ± SEM. *P < 0.05, **P < 0.01, NS, non-significant (n = 3 independent experiments).

Original languageEnglish
Article number122752
JournalBiomaterials
Volume312
DOIs
StatePublished - Jan 2025
Externally publishedYes

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