Correcting the record of structural publications requires joint effort of the community and journal editors

  • Bernhard Rupp
  • , Alexander Wlodawer
  • , Wladek Minor
  • , John R. Helliwell
  • , Mariusz Jaskolski

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations

Abstract

Seriously flawed and even fictional models of biomolecular crystal structures, although rare, still persist in the record of structural repositories and databases. The ensuing problems of database contamination and persistence of publications based on incorrect structure models must be effectively addressed. The burden cannot be simply left to the critical voices who take the effort to contribute dissenting comments that are mostly ignored. The entire structural biology community, and particularly the journal editors who exercise significant power in this respect, must engage in a constructive dialog lest structural biology lose its credibility as an evidence-based empirical science.

Original languageEnglish
Pages (from-to)4452-4457
Number of pages6
JournalFEBS Journal
Volume283
Issue number24
DOIs
StatePublished - 1 Dec 2016
Externally publishedYes

Keywords

  • X-ray crystal structure models
  • biomolecular crystallography
  • database integrity
  • error correction
  • structural databases

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