Coronary Artery Disease in Patients ≥80 Years of Age

Mahesh V. Madhavan; Bernard J. Gersh; Karen P. Alexander; Christopher B. Granger; Gregg W. Stone

doi:10.1016/j.jacc.2017.12.068

Coronary Artery Disease in Patients ≥80 Years of Age

Mahesh V. Madhavan, Bernard J. Gersh, Karen P. Alexander, Christopher B. Granger, Gregg W. Stone

Research output: Contribution to journal › Review article › peer-review

183 Scopus citations

Abstract

Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients ≥80 years of age. Nonetheless, older patients have typically been under-represented in cardiovascular clinical trials. Understanding the pathophysiology, epidemiology, and optimal means of diagnosis and treatment of CAD in older adults is crucial to improving outcomes in this high-risk population. A patient-centered approach, taking into account health status, functional ability and frailty, cognitive skills, and patient preferences is essential when caring for older adults with CAD. The present systematic review focuses on the current knowledge base, gaps in understanding, and directions for future investigation pertaining to CAD in patients ≥80 years of age.

Original language	English
Pages (from-to)	2015-2040
Number of pages	26
Journal	Journal of the American College of Cardiology
Volume	71
Issue number	18
DOIs	https://doi.org/10.1016/j.jacc.2017.12.068
State	Published - 8 May 2018
Externally published	Yes

Keywords

coronary artery disease
geriatric cardiology
octogenarians

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title = "Coronary Artery Disease in Patients ≥80 Years of Age",

abstract = "Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients ≥80 years of age. Nonetheless, older patients have typically been under-represented in cardiovascular clinical trials. Understanding the pathophysiology, epidemiology, and optimal means of diagnosis and treatment of CAD in older adults is crucial to improving outcomes in this high-risk population. A patient-centered approach, taking into account health status, functional ability and frailty, cognitive skills, and patient preferences is essential when caring for older adults with CAD. The present systematic review focuses on the current knowledge base, gaps in understanding, and directions for future investigation pertaining to CAD in patients ≥80 years of age.",

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AU - Gersh, Bernard J.

AU - Alexander, Karen P.

AU - Granger, Christopher B.

AU - Stone, Gregg W.

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AB - Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients ≥80 years of age. Nonetheless, older patients have typically been under-represented in cardiovascular clinical trials. Understanding the pathophysiology, epidemiology, and optimal means of diagnosis and treatment of CAD in older adults is crucial to improving outcomes in this high-risk population. A patient-centered approach, taking into account health status, functional ability and frailty, cognitive skills, and patient preferences is essential when caring for older adults with CAD. The present systematic review focuses on the current knowledge base, gaps in understanding, and directions for future investigation pertaining to CAD in patients ≥80 years of age.

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Coronary Artery Disease in Patients ≥80 Years of Age

Abstract

Keywords

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